Pluronic修饰脂质体的研究进展

材料导报

2021, Vol. 35

Issue (z2): 612-615

高分子与聚合物基复合材料

Pluronic修饰脂质体的研究进展

李文娟, 廖璇, 熊向源, 龚妍春, 李资玲

江西科技师范大学生命科学学院,南昌 330013

Research Progress of Pluronic Modified Liposomes

LI Wenjuan, LIAO Xuan, XIONG Xiangyuan, GONG Yanchun, LI Ziling

School of Life Science, Jiangxi Science & Technology Normal University, Nanchang 330013, China

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摘要采用不同材料对脂质体表面进行修饰已成为脂质体的研究热点。Pluronic是非离子表面活性剂,具有很好的生物相容性,常用作药物载体。本文从Pluronic修饰脂质体的制备工艺,理化性质及其载体的运用三方面进行综述,为修饰脂质体的进一步开发提供一定的参考。

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关键词: Pluronic 脂质体理化性质载体

Abstract: The surface modification of liposomes with different materials has been hot in liposomal research. Pluronic is a nonionic surfactant with good biocompatibility and is commonly used as drug carrier. The preparation method of Pluronic modified liposomes, physicochemical properties and carrier application were reviewed in this paper, which will provide some references for the further development of Pluronic modified liposomes.

Key words: pluronic liposomes physicochemical properties carrier

发布日期: 2021-12-09

ZTFLH:

TB324

基金资助: 国家自然科学基金(21766008);江西省自然科学基金(20202BAB205012);江西科技师范大学博士科研启动基金(2019BSQD012);江西科技师范大学研究生创新专项资金(YC2021-X16)

通讯作者: lzlowen2010@gmail.com

作者简介: 李文娟,2020年毕业于济宁学院生物制药专业,现为江西科技师范大学生命科学学院硕士研究生,主要从事高分子生物医药材料的研究。
李资玲,博士,江西科技师范大学副教授,主要从事纳米级高分子药物载体的研究。在Journal of Controlled Release、Food Research Internatio-nal等期刊上发表了10余篇 SCI 论文。获得2013年度江西省高等学校科技成果奖二等奖,2009 年度江西省自然科学奖三等奖。

引用本文:

李文娟, 廖璇, 熊向源, 龚妍春, 李资玲. Pluronic修饰脂质体的研究进展[J]. 材料导报, 2021, 35(z2): 612-615.
LI Wenjuan, LIAO Xuan, XIONG Xiangyuan, GONG Yanchun, LI Ziling. Research Progress of Pluronic Modified Liposomes. Materials Reports, 2021, 35(z2): 612-615.

链接本文:

http://www.mater-rep.com/CN/ 或 http://www.mater-rep.com/CN/Y2021/V35/Iz2/612

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