Four compounds (4-hydroxy-2-methyl-5-methylthio benzyl acrylamide (A), 2-hydroxy-4-acrylamide methyl-5-methylthio-6-methyl benzyl acrylamide (B), 3-acrylamide methyl-2-hydroxy benzamide (C), 1-acrylamide methyl-2-naphthol (D)) containing capsaicin moieties were synthesized with substituted aromatic and N-methylol acrylamide by Friedel-Crafts alkylation reaction, and their structures were characterized by infrared spectroscopy (IR) and hydrogen nuclear magnetic spectra ( 1H NMR). The results of antibacterial test showed that the best inhibitory activity can be observed on Staphylococcus aureus and Escherichia coli with compound D, reaching the minimum inhibitory concentration (MIC) of 0.187 5 mg/mL. Moreover, the inhibitory activity of D on the two tested algae performed the best. The resins synthesized with four compounds as functional monomers were verified to have great inhibitory activity on tested algae. Besides, the best inhibitory activity is obtained on resin comprised of compound D, which has the inhibition rate of over 50% after 72 h.
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