Abstract: Molecular imprinting technology is a new molecular recognition technology by which the polymers with specific and selective recognition ability could be prepared. With high specificity, stability and repeatability, it has gradually become the research hotspot. Chitosan is an environment-friendly, abundant and recyclable natural polymer compound. The amino functional groups in molecular structure of chitosan have strong activity, which makes chitosan have various unique properties such as biodegradability, cell affinity and biological effects. It is widely used in the fields of medicine, food and environmental protection. The functional group of chitosan has strong reaction activity and is easy to be chemically modification. Combined with molecular imprinting technology, the chitosan and its derivatives could be taken as functional monomers or carriers for preparing new molecular imprinting polymers with ideal affinity and stability, high imprinting efficiency and strong selectivity, which can improve the properties of chitosan materials and broaden its application field and scope. According to the research progress in the field of molecular imprinting modification of chitosan, the role of chitosan and its derivatives in the preparation of molecular imprinting polymers, the preparation methods of molecular imprinting polymers and the types of common crosslinking agents were summarized. The applications of chitosan molecular imprinting polymers in the treatment of heavy metal pollutants, biomedicine, solid phase extraction, protein recognition, electrochemical sensor and chiral material separation were expounded in detail. The advantages and disadvantages of chitosan molecular imprinting polymers in various fields were analyzed. The development direction of chitosan molecular imprinting technology was prospected.
作者简介: 冯颖,沈阳化工大学教授、硕士研究生导师。2005年毕业于天津大学,获工学博士学位。主要从事非均相分离技术、工艺和新材料的研究,主持完成国家自然科学基金项目、辽宁省自然科学基金项目等多项科研课题。在《化工进展》《复合材料学报》《精细化工》等核心期刊发表论文30篇。 董鑫,沈阳化工大学讲师、硕士研究生导师。2019年9月在大连理工大学化工学院取得博士学位。主要从事生物膜多孔介质材料中流体流动行为与输运特性、环境流体多相流传递理论与技术的研究工作。曾先后参与国家自然科学基金项目、辽宁省科技厅项目的研究工作,主持辽宁省自然科学基金项目。在Chemical Engineering Research and Design、Chemical Engineering and Technology、 《化工学报》等国内外核心期刊发表研究论文20篇。
引用本文:
冯颖, 李齐雪, 邵娟, 张建伟, 董鑫, 张庆瑾. 基于壳聚糖的分子印迹技术研究及应用[J]. 材料导报, 2022, 36(17): 21040121-8.
FENG Ying, LI Qixue, SHAO Juan, ZHANG Jianwei, DONG Xin, ZHANG Qingjin. Research and Application of Molecular Imprinting Technology Based on Chitosan. Materials Reports, 2022, 36(17): 21040121-8.
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