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材料导报  2022, Vol. 36 Issue (22): 20100133-12    https://doi.org/10.11896/cldb.20100133
  无机非金属及其复合材料 |
生物质碳点荧光材料在生物医药领域中的应用
安玉龙, 刘灿*, 徐开蒙, 郑云武, 林旭*
西南林业大学林业生物质资源高效利用技术国家地方联合工程研究中心,西南地区林业生物质资源高效利用国家林业和草原局重点实验室,昆明 650224
Application of Biomass Carbon Dot Fluorescence Materials in Biomedical Field
AN Yulong, LIU Can*, XU Kaimeng, ZHENG Yunwu, LIN Xu*
Key Laboratory of National Forestry and Grassland Administration for Highly-efficient Utilization of Forest Biomass Resources in the Southwest China, National Joint Engineering Research Center for Highly-efficient Utilization Technology of Forest Biomass Resources, Southwest Forestry University, Kunming 650224, China
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摘要 荧光材料由于具有特殊的光学性质,在生物医学、生物成像和荧光传感等相关领域有广泛的应用。与传统的荧光剂相比,纳米荧光材料具有稳定性好、荧光强度高等优点。然而,传统的荧光纳米材料通常含有重金属,使其在生物医药领域中的应用受到限制。生物质荧光碳点作为一种新型的荧光碳纳米材料,因具有优异的生物相容性、化学惰性、荧光可调节性,在生物医药、生物传感、荧光成像等多个领域展现出应用潜力。但是,目前生物质碳点应用于生物医药领域的综述文献相对较少。因此,本文总结了不同天然产物制备碳点的绿色合成方法,对碳点的荧光机理进行了分析和归纳,重点阐述了碳点在生物传感、生物成像、药物载体、生物抗菌剂等生物医药领域的应用研究,讨论了存在的问题,并对碳点在该领域的发展方向进行了展望。
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安玉龙
刘灿
徐开蒙
郑云武
林旭
关键词:  生物质  荧光碳点  合成方法  荧光发射机理    
Abstract: Due to its special optical properties, fluorescent materials have been widely used in biomedicine, biological imaging, fluorescence sensing and other related fields. Compared with traditional fluorescent agents, nano-fluorescent materials have the advantages of good stability and high fluorescence intensity. However, traditional semiconductor nano-fluorescent materials often contain heavy metals, which limits their application in biomedical fields. As a new type of fluorescent carbon nanomaterials, biomass fluorescent carbon dots (CDs) have some favorable characteristics such as biocompatibility, chemical inertness and fluorescence regulation, which have potential applications in biomedicine, biosensor, fluorescence imaging and other fields. At present, there are relatively few studies on the application of biomass CDs in biomedicine field. Therefore, this article summarized the green synthesis methods of different natural products to prepare CDs, and analyzed the fluorescence mechanism of CDs. It focused on the application of CDs in biomedical fields such as biosensors, biological imaging, drug carriers and biological antibacterial agents, discussed the existing problems, and looked forward to its future development direction in this field.
Key words:  biomass    fluorescent carbon dot    synthesis method    fluorescence emission mechanism
出版日期:  2022-11-25      发布日期:  2022-11-25
ZTFLH:  TQ352.1  
基金资助: 国家自然科学基金地区基金项目(21961036);国家重点研发计划课题(2019YFD1002404);云南省农业联合重点项目(2017FG001-001)
通讯作者:  * liucanswfu@163.com; linxunefu@126.com   
作者简介:  安玉龙,2019年6月毕业于山东农业工程学院,获得理学学士学位。现为西南林业大学材料科学与工程学院硕士研究生,在林旭和刘灿导师的指导下进行生物质碳材料的研究。目前主要从事生物质荧光碳纳米点材料的研究。
林旭,研究员,分别于2004年、2009年毕业于东北林业大学理学院并获得学士与硕士学位;2012年毕业于日本千叶大学,获得理学博士学位。目前从事生物基功能材料与新型纳米材料的制备与应用。已在Chemical Communications、Chemistry-A European Journal、Journal of Materials Chemistry A等国外知名杂志发表学术论文20余篇,其中以第一作者或通讯作者的论文8篇,累积影响因子达到40。
刘灿,西南林业大学副教授、硕士研究生导师。分别于2006年、2009年毕业于东北农业大学并获得学士与硕士学位;2013年毕业于东北林业大学,获得生物材料工程博士学位。现为西南林业大学材料科学与工程学院高分子材料与工程专业系主任,中国林学会活性炭专业委员会常委、云南省塑料行业协会副秘书长。长期从事先进碳材料(生物基碳量子点、生物基碳纤维、活性炭等)、生物基高性能树脂、生物基纤维等方面的研究。已发表论文50余篇,近三年SCI、EI收录13余篇,核心8篇,获授权专利14项,发明专利2项,国际领先成果2项,编写云南省地方规程3项,国家标准2项。
引用本文:    
安玉龙, 刘灿, 徐开蒙, 郑云武, 林旭. 生物质碳点荧光材料在生物医药领域中的应用[J]. 材料导报, 2022, 36(22): 20100133-12.
AN Yulong, LIU Can, XU Kaimeng, ZHENG Yunwu, LIN Xu. Application of Biomass Carbon Dot Fluorescence Materials in Biomedical Field. Materials Reports, 2022, 36(22): 20100133-12.
链接本文:  
http://www.mater-rep.com/CN/10.11896/cldb.20100133  或          http://www.mater-rep.com/CN/Y2022/V36/I22/20100133
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