纳米纤维基智能创伤敷料的研究进展

doi:10.11896/cldb.23060224

材料导报

2024, Vol. 38

Issue (20): 23060224-11 https://doi.org/10.11896/cldb.23060224

高分子与聚合物基复合材料

纳米纤维基智能创伤敷料的研究进展

周美玲¹, 杜姗¹, 欧康康^1,2,3,*, 代云玲¹, 齐琨¹, 王华平²

1 中原工学院先进纺织装备技术省部共建协同创新中心,郑州 451191
2 东华大学纤维材料改性国家重点实验室,上海 201620
3 上海工程技术大学纺织服装学院,上海 201620

Recent Progress of Smart Wound Dressings Based on Nanofibers

ZHOU Meiling¹, DU Shan¹, OU Kangkang^1,2,3,*, DAI Yunling¹, QI Kun¹, WANG Huaping²

1 Advanced Textile Equipment Technology Co-construction Collaborative Innovation Center, Zhongyuan University of Technology, Zhengzhou 451191, China
2 State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Donghua University, Shanghai 201620, China
3 School of Textiles and Fashion, Shanghai University of Engineering Science, Shanghai 201620, China

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摘要针对当前创面修复的高需求和现代商业敷料发展不充分之间的矛盾,通过敷料的实时监测、感染预警和按需给药功能来减轻患者痛苦、加速创面愈合成为亟待解决的问题。基于纳米纤维的特性及其在创伤修复中起到的关键作用,围绕纳米纤维基智能创伤敷料的制备及响应体系,阐述了纳米纤维基智能创伤敷料的制备方法、创面微环境标志物监测体系以及敷料自响应药物缓释体系等多个领域的研究进展。最后,从理想敷料的特性、生物相容性、多功能监测和远程医疗等方面,探讨了未来纳米纤维基智能创伤敷料面临的挑战和发展趋势。

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	周美玲
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	齐琨
	王华平

关键词: 纳米纤维静电纺丝创伤敷料智能监测智能给药

Abstract: In view of the contradiction between the current high demand for wound repair and the insufficient development of contemporary commercial dressings, it is expected to alleviate the pain of patients and accelerate wound healing through real-time monitoring, infection warning and on-demand administration of dressings. Based on the characteristics of nanofibers and their key role in wound repair, the preparation and response system of nanofiber-based intelligent wound dressings are reviewed. The preparation methods of nanofiber-based intelligent wound dres-sings, the detection system of wound microenvironment markers and the self-responsive drug delivery system of dressings are described. Finally, the future challenges and development trends of nanofiber-based smart wound dressings are discussed from the perspectives of the characteristics and biocompatibility of ideal dressings, as well as multifunctional monitoring and telemedicine.

Key words: nanofibers electrospinning wound dressing intelligent monitoring smart drug delivery

出版日期: 2024-10-25 发布日期: 2024-11-05

ZTFLH:

TS 101.4

基金资助: 国家自然科学基金(52003048);河南省高等学校重点科研项目(23A540001;22A540002);中国纺织工业联合会科技指导项目(2021020);中原工学院优势学科实力提升计划项目(SD202219;SD202221;SD202222);中原工学院青年自然科学基金项目(K2022QN013);中原工学院青年骨干教师项目(2021XQG02)

通讯作者: * 欧康康,上海工程技术大学副教授、硕士研究生导师、高层次引进D类人才。2018年博士毕业于东华大学纺织化学与染整工程专业。目前主要从事功能性纺织材料的结构设计、开发及应用研究工作。参与国家重点研发计划、国家自然科学基金项目3项;在Nano Energy、Chemical Enginee-ring Journal、ACS Applied Materials & Interfaces、Materials and Design、Cellulose、《纺织学报》等中英文杂志上发表高水平学术论文30余篇,获授权发明专利10余项。oukang1990@163.com

作者简介: 周美玲,2017年6月于中原工学院获得工学学士学位。现为中原工学院纺织学院硕士研究生,在欧康康副教授指导下进行研究。目前主要研究领域为生物医用纳米纤维材料。

引用本文:

周美玲, 杜姗, 欧康康, 代云玲, 齐琨, 王华平. 纳米纤维基智能创伤敷料的研究进展[J]. 材料导报, 2024, 38(20): 23060224-11.
ZHOU Meiling, DU Shan, OU Kangkang, DAI Yunling, QI Kun, WANG Huaping. Recent Progress of Smart Wound Dressings Based on Nanofibers. Materials Reports, 2024, 38(20): 23060224-11.

链接本文:

http://www.mater-rep.com/CN/10.11896/cldb.23060224 或 http://www.mater-rep.com/CN/Y2024/V38/I20/23060224

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