丝素蛋白复合石墨烯类材料在生物医学领域中的研究进展

材料导报

2020, Vol. 34

Issue (Z1): 511-515

高分子与聚合物基复合材料

丝素蛋白复合石墨烯类材料在生物医学领域中的研究进展

方敏, 王璐, 侯佳欣, 南晓茹, 赵彬

山西医科大学口腔医学院,太原 030001

Research Progress of Composites Based on Silk Fibroin/Graphene Materials forBiomedical Applications

FANG Min, WANG Lu, HOU Jiaxin, NAN Xiaoru, ZHAO Bin

School of Stomatology, Shanxi Medical University, Taiyuan 030001, China

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摘要丝素蛋白是一种天然生物聚合物,因其具有独特的弹性、柔韧性、生物相容性和生物可降解性而在生物医学领域有很大的应用潜力。然而,低成骨能力和力学性能不足限制了其在骨科等领域的应用。
石墨烯是一种碳质新材料,具有强度高、延展性能优良以及导热系数高、电子迁移率高和电阻率低等特性。以氧化石墨烯、还原氧化石墨烯为代表的石墨烯类纳米材料在保持石墨烯特性的基础上,又分别被赋予了良好的水溶性、生物相容性及电化学活性等卓越的理化性能,近年来已成为生物医学领域的研究热点。研究发现,将丝素蛋白与石墨烯类材料联合应用,可结合各自特点以制备出性能更优的复合材料,从而开辟更广阔的应用前景。
本文综述了丝素蛋白复合石墨烯类材料的制备方法、性能及其在生物医学领域的应用,并展望了此类复合材料在生物医学领域未来的发展趋势。

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关键词: 丝素蛋白石墨烯氧化石墨烯还原氧化石墨烯复合材料生物医学

Abstract: Silk fibroin is a natural biopolymer with strong potential for biomedical applications due to its extraordinary characteristics including elasticity, flexibility, biocompatibility and biodegradability. However, the low osteogenic capacity and mechanical property deficiency have limited applications for silk fibroin in the orthopedic area. Graphene is a new carbon material. Nano-materials based on graphene such as graphene oxide and reduced graphene oxide have excellent physical and chemical properties, which have become a hot research topic in biomedical field in recent years. Composite materials with better performance can be produced by combing such two materials with their own characteristics, which could open up a wider application prospect. In this paper, the preparation methods and properties of silk fibroin/graphene composites and their applications in biomedical field are reviewed. Moreover, the future development of these composites in biomedical field is prospected.

Key words: silk fibroin graphene graphene oxide reduced graphene oxide composite materials biomedical application

发布日期: 2020-07-01

ZTFLH:	TB33
	Q819

基金资助: 山西省重点研发计划项目(201803D121041);山西省应用基础研究项目(201701D221065);山西医科大学校博士启动基金(BS03201638)

作者简介: 方敏,2009年6月毕业于南通大学医学院,获得口腔医学学士学位。现为山西医科大学口腔临床医学硕士研究生,在赵彬教授的指导下开展研究。目前主要研究领域为组织工程支架在口腔颌面部组织修复中的研发与应用;赵彬,山西医科大学口腔医学院(口腔医院)院长,教授,博士研究生导师。主持并参与省部级科研项目10余项,1项国家自然基金,获得专利1项,发表SCI论文11篇,在国家和省级学术刊物上发表论文数100余篇。主持第四次全国口腔健康流行病学调查山西地区的流调工作,为口腔医学的发展做出了贡献。获得山西省科学技术进步奖二等奖、山西省高等学校技术进步二等奖等奖励。

引用本文:

方敏, 王璐, 侯佳欣, 南晓茹, 赵彬. 丝素蛋白复合石墨烯类材料在生物医学领域中的研究进展[J]. 材料导报, 2020, 34(Z1): 511-515.
FANG Min, WANG Lu, HOU Jiaxin, NAN Xiaoru, ZHAO Bin. Research Progress of Composites Based on Silk Fibroin/Graphene Materials forBiomedical Applications. Materials Reports, 2020, 34(Z1): 511-515.

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http://www.mater-rep.com/CN/ 或 http://www.mater-rep.com/CN/Y2020/V34/IZ1/511

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