Abstract: In the present study, Ag-doped glass antimicrobial material containing a high proportion of zinc oxide was developed by high temperature melting method, in which the silver as antimicrobial active ingredient. By means of scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and X-ray diffraction (XRD), the material is amorphous, consisting of B, O, Na, Si, Ca, Zn and Ag elements. The dissolubility of Ag+ was investigated by atomic absorption spectrometry (AAS).It was found that the amount of Ag+ released was increased with time, but the release rate decreased while Ag+ concentration in solution increased. Moreover, it is also affected by the amount of material, the less the material used, the higher the proportion of Ag+ dissolution. The antimicrobial material shows a good performance of stable and slow release of Ag+. Escherichia coli and Staphylococcus aureus were used to value the antimicrobial activities. The results showed that the growth of bacteria around the antimicrobial material was obviously inhibited and transparent bacteriostasis circles were formed. The results of IR absorption spectra showed that ZnO participated in the glass network structure in the form of [ZnO4] tetrahedron and formed Zn-O-B and Zn-O-Si bonds.
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