State of Research into Fluorescent Biosensors for the Simultaneous Detection of Multiple Mycotoxins
SUN Qingyue1, YU Tao2, PENG Shuangfeng2, KONG Dezhao3, LIU Chang3, SHI Qiaoqiao3, LI Yaqi3,4,5,*, CHEN Yong5,*
1 School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212100, Jiangsu, China 2 School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang 212100, Jiangsu, China 3 School of Grain Science and Technology, Jiangsu University of Science and Technology, Zhenjiang 212100, Jiangsu, China 4 Suzhou Zhongke Advanced Technology Research Institute Co., Ltd., Suzhou 215123, Jiangsu, China 5 School of Environmental Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China
Abstract: Mycotoxins are secondary metabolites produced by fungi. The three largest groups are aflatoxins, fumonisins, and ochratoxins. Food pro-ducts are susceptible to mycotoxin contamination during storage, processing, and transportation. In most cases, multiple mycotoxins occur simultaneously and create a superimposed effect that can be highly toxic, causing food safety problems and posing a serious health risk to humans. Simultaneous detection of multiple mycotoxins in food would be extremely helpful. This paper reviews the progress of research into the development of fluorescent biosensors for the detection of mycotoxins both domestically and abroad, with particular focus on multiplexed and simultaneous detection of mycotoxins, especially the types and composition of fluorescent biosensors. It also addresses detection methods and strategies involving aptamer and immunoassay techniques. The limitations and challenges of existing mycotoxin detection are discussed, and directions for future research are outlined with a view to providing theoretical support for mycotoxin detection research.
孙青月, 余涛, 彭双凤, 孔德昭, 刘畅, 史巧巧, 李雅琪, 陈勇. 荧光生物传感器用于多种真菌毒素同时检测的研究进展[J]. 材料导报, 2024, 38(10): 22090139-11.
SUN Qingyue, YU Tao, PENG Shuangfeng, KONG Dezhao, LIU Chang, SHI Qiaoqiao, LI Yaqi, CHEN Yong. State of Research into Fluorescent Biosensors for the Simultaneous Detection of Multiple Mycotoxins. Materials Reports, 2024, 38(10): 22090139-11.
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