层层自组装技术在组织工程领域的研究进展

材料导报

2019, Vol. 33

Issue (Z2): 538-541

高分子与聚合物基复合材料

层层自组装技术在组织工程领域的研究进展

郭雨晴, 张菁, 李颂

安徽医科大学,安徽医科大学口腔医学院,安徽医科大学附属口腔医院,安徽省口腔疾病研究中心实验室,合肥 230032

Research Progress of Layer-by-layer Self-assembly Technology in the Field of TissueEngineering

GUO Yuqing, ZHANG Jing, LI Song

Anhui Province Key Laboratory of Oral Diseases, the Affiliated Stomatological Hospital of Anhui Medical University, Research Stomatological College of Anhui Medical University, Anhui Medical University, Hefei 230032

摘要
参考文献
相关文章
推荐阅读
Metrics

下载:

全文 ( PDF ) ( 1520KB )
输出: BibTeX | EndNote (RIS)

摘要层层自组装(Layer-by-layer self-assembly,LBL)是利用逐层交替沉积的方法,借助各层分子间的弱相互作用,使层与层自发地缔合形成结构完整、性能稳定、具有某种特定功能的分子聚集体或超分子结构的过程。组织工程学被称为“再生医学”,是指利用生物活性物质,通过体外培养或构建的方法,再造或者修复器官及组织的技术,其主要包括新型生物材料、细胞来源、信号因子和生物制造方法等四个方面,目标是制造功能组织,用于再生医学和药物试验。本文就层层自组装技术在组织工程领域的研究进展进行综述。

	服务
	把本文推荐给朋友
	加入引用管理器
	E-mail Alert
	RSS
	作者相关文章
	郭雨晴
	张菁
	李颂

关键词: 层层自组装(LBL) 组织工程再生医学

Abstract: Layer-by-layer self-assembly (LBL) is a method of layer by layer alternating deposition. According to the weak interactions between the layer of molecules, the layers spontaneously joined together to form a molecular aggregate or supramolecular structure which has a complete structure and stable performance. Tissue engineering is called "regenerative medicine", which refers to the technology of reconstructing or repairing organs and tissues by means of bioactive substances and in vitro culture or construction. It mainly includes four aspects: new biomaterials, cell sources, signal factors and biological manufacturing methods. The aim is to manufacture functional tissues for use in regenerative medicine and drug testing. In this paper, the research progress of layer-by-layer self-assembly in tissue engineering is reviewed.

Key words: layer-by-layer self-assembly (LBL) tissue engineering regenerative medicine

出版日期: 2019-11-25 发布日期: 2019-11-25

ZTFLH:

TB34

基金资助: 国家自然科学基金(81400497)

通讯作者: 3197053337@qq.com

作者简介: 郭雨晴,安徽医科大学口腔临床医学硕士研究生,本科毕业于安徽省皖南医学院。于2019年6月以第一作者身份在中文核心期刊上发表文章一篇。研究重点主要围绕骨组织再生,并且跟随研究生导师在临床上从事牙体牙髓专业方面的技能。
李颂,博士,教授。1994年获湖北医科大学硕士学位,2004年获华西医科大学口腔医学博士,2009年晋升教授职称,任硕士研究生导师。1994年至今于安徽医科大学口腔系从事教学、科研和临床工作。主要研究领域:儿童口腔变形链球菌的检出情况及和母亲的关系;儿童口腔变形链球菌的传播及影响因素;变链素产生的临床意义研究;变链素的纯化和序列测定、基因克隆;牙体牙髓病的临床研究。

引用本文:

郭雨晴, 张菁, 李颂. 层层自组装技术在组织工程领域的研究进展[J]. 材料导报, 2019, 33(Z2): 538-541.
GUO Yuqing, ZHANG Jing, LI Song. Research Progress of Layer-by-layer Self-assembly Technology in the Field of TissueEngineering. Materials Reports, 2019, 33(Z2): 538-541.

链接本文:

http://www.mater-rep.com/CN/ 或 http://www.mater-rep.com/CN/Y2019/V33/IZ2/538

1 Decher G, Hong J D. Makromolekulare Chemie Macromolecular Symposia,1991,46(1),321.
2 Xing J, Mei T, Luo K, et al. Acta Biomaterialia,2017,53,470.
3 Wang H, He X Q, Jin T, et al. Stem Cell Research & Therapy,2016,7(1),1.
4 Wan W, Zhang S, Ge L, et al. International Journal of Nanomedicine,2015,1273.
5 Xing H, Wang X, Xiao S, et al. International Journal of Nanomedicine,2017,12,7709.
6 Liu X, Han F, Zhao P, et al. Nanomedicine,2017,13(4),1423.
7 Gentile P, Ghione C, Ferreira A M, et al. Biomaterials Science,2017,5,1922.
8 Hsieh Y H, Shen B Y, Wang Y H, et al. International Journal of Mole-cular Medicine,2018,19(4),1125.
9 Guo P, Shi Z L, Liu A, et al. International Journal of Molecular Sciences,2014,15(11),20117.
10 Menu P, Stoltz J F, Kerdjoudj H. Biomedical Materials and Engineering,2012,22,17.
11 Shima F, Narita H, Hiura A, et al. Journal of Biomedical Materials Research Part A,2017,105,814.
12 Amano Y, Nishiguchi A, Matsusak M, et al. Acta Biomaterialia,2016,33,110.
13 Liu G, Li L, Huo D, et al. Biomaterials,2017,127,117.
14 Qian Y, Zhao X, Han Q, et al. Nature Communications,2018,9,323.
15 Monfared A, Ghaee A, Ebrahimi-Barough S, et al. Colloids Surface B Biointerfaces,2018,170,617.
16 Li W, Guan T,Zhang X, et al. ACS Applied Materials & Interfaces,2015,7(5),3018.,
17 Mahjour S B, Fu X, Yang X, et al. Burns,2015,41(8),1764.
18 Kong Y, Xu R, Darabi M A, et al. International Journal of Nanomedicine,2016,11,2543.
19 Gu L, Deng Z J, Roy S, et al. Clinical Cancer Research An Official Journal of the American Association for Cancer Research,2017,23,7312.
20 Teng W, Wang Q, Chen Y, et al. International Journal of Nanomedicine,2014,9,5013.

[1]	晋艳茹, 贾庆明, 陕绍云. 羟基磷灰石/纤维素复合材料在骨组织工程中的研究进展[J]. 材料导报, 2019, 33(23): 4008-4015.
[2]	钟红荣, 张岩, 包红, 方艳, 吴婷芳, 朱勇, 张小宁, 徐水. 丝素/明胶/壳聚糖支架材料的构建及表征[J]. 材料导报, 2018, 32(22): 3954-3960.
[3]	胡建新, 李凤清, 周雪琴, 刘东志, 汪天洋, 李巍. 卟啉-多肽超分子组装体系的研究进展^*[J]. 《材料导报》期刊社, 2017, 31(11): 128-137.

[1]	Dongyong SI, Guangxu HUANG, Chuanxiang ZHANG, Baolin XING, Zehua CHEN, Liwei CHEN, Haoran ZHANG. Preparation and Electrochemical Performance of Humic Acid-based Graphitized Materials[J]. Materials Reports, 2018, 32(3): 368 -372 .
[2]	Bingwei LUO,Dabo LIU,Fei LUO,Ye TIAN,Dongsheng CHEN,Haitao ZHOU. Research on the Two Typical Infrared Detection Materials Serving at Low Temperatures: a Review[J]. Materials Reports, 2018, 32(3): 398 -404 .
[3]	Huimin PAN,Jun FU,Qingxin ZHAO. Sulfate Attack Resistance of Concrete Subjected to Disturbance in Hardening Stage[J]. Materials Reports, 2018, 32(2): 282 -287 .
[4]	Siyuan ZHOU,Jianfeng JIN,Lu WANG,Jingyi CAO,Peijun YANG. Multiscale Simulation of Geometric Effect on Onset Plasticity of Nano-scale Asperities[J]. Materials Reports, 2018, 32(2): 316 -321 .
[5]	Xu LI,Ziru WANG,Li YANG,Zhendong ZHANG,Youting ZHANG,Yifan DU. Synthesis and Performance of Magnetic Oil Absorption Material with Rice Chaff Support[J]. Materials Reports, 2018, 32(2): 219 -222 .
[6]	Ninghui LIANG,Peng YANG,Xinrong LIU,Yang ZHONG,Zheqi GUO. A Study on Dynamic Compressive Mechanical Properties of Multi-size Polypropylene Fiber Concrete Under High Strain Rate[J]. Materials Reports, 2018, 32(2): 288 -294 .
[7]	WANG Tong, BAO Yan. Advances on Functional Polyacrylate/Inorganic Nanocomposite Latex for Leather Finishing[J]. Materials Reports, 2017, 31(1): 64 -71 .
[8]	WANG Wenjin, WANG Keqiang, YE Shenjie, MIAO Weijun, CHEN Zhongren. Effect of Asymmetric Block Copolymer of PI-b-PB on Phase Morphology and Properties of IR/BR Blends[J]. Materials Reports, 2017, 31(2): 96 -100 .
[9]	HUANG Dajian, MA Zonghong, MA Chenyang, WANG Xinwei. Preparation and Properties of Gelatin/Chitosan Composite Films Enhanced by Chitin Nanofiber[J]. Materials Reports, 2017, 31(8): 21 -24 .
[10]	WU Tao, MAO Lili, WANG Haizeng. Preparation and Defluoridation Performance of Mg/Fe-LDHO/PES Membranous Adsorbent[J]. Materials Reports, 2017, 31(14): 26 -30 .

Viewed

Full text

Abstract

Cited

Shared

Discussed