Please wait a minute...
材料导报  2021, Vol. 35 Issue (Z1): 87-93    
  无机非金属及其复合材料 |
无机纳米颗粒在癌症治疗中的研究进展
邬欣1, 曾利胜2, 王剑龙1, 李建3
1 中南大学湘雅三医院骨科,长沙410013
2 湖南省保靖县人民医院骨科,湘西 416500
3 中南大学湘雅三医院输血科,长沙410013
Research Progress of Inorganic Nanoparticles in Cancer Therapy
WU Xin1, ZENG lisheng2, WANG Jianlong1, LI Jian3
1 Department of Spinal Surgery, Third Xiangya Hospital, Central South University, Changsha 410013, China
2 Department of Orthopedics Department, Baojing People's Hospital of Hunan Province, Xiangxi 416500, China
3 Department of Blood Transfusion, Third Xiangya Hospital, Central South University, Changsha 410013, China
下载:  全 文 ( PDF ) ( 2550KB ) 
输出:  BibTeX | EndNote (RIS)      
摘要 纳米材料在癌症治疗中具有重要的意义。近年来,纳米材料的研究涉及多个领域,包括药物传递、疫苗开发、抗菌、诊断、癌症治疗和成像工具等。纳米材料分为有机纳米材料和无机纳米材料,无机纳米材料因其独特的尺寸依赖性的物理化学性质和特殊的光学/电磁学特性而受到广泛关注,而这是有机纳米材料所不具备的。在癌症治疗中,选择合适的无机纳米材料与搭配方法将为治疗带来更好的效果。
服务
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章
邬欣
曾利胜
王剑龙
李建
关键词:  癌症治疗  无机纳米颗粒  纳米医学    
Abstract: Nanoparticles plays an important role in cancer therapy. In recent years, Nanoparticles have been studied in a number of areas, including drug delivery, vaccine development, antimicrobial, diagnostic, cancer treatment and imaging tools. Nanoparticles are divided into organic nanoparticles and inorganic nanoparticles. Inorganic nanoparticles are widely concerned because of their unique materials, size-dependent physical-chemical properties and special optical/electromagnetic properties, which are not possessed by organic nanoparticles. In cancer therapy, the choice of appropriate method of inorganic nanoparticles and collocation will bring better results for treatment.
Key words:  cancer therapy    inorganic nanoparticles    nanomedicine
                    发布日期:  2021-07-16
ZTFLH:  TB34  
基金资助: 2020 年中南大学研究生科研创新项目(2020zzts896)
通讯作者:  lj168301018@csu.edu.cn;13787073787@139.com   
作者简介:  邬欣,2019 年 6月毕业于南华大学,获得临床医学学士学位。现为中南大学湘雅三医院硕士研究生,在王剑龙教授和李建老师的指导下进行研究。目前主要研究领域为纳米材料在癌症治疗中的应用,主持中南大学研究生自主创新课题。王剑龙,医学博士,主任医师,硕士研究生导师。中南大学脊柱微创研究中心副主任。湖南省健康服务业协会第一届脊柱健康分会副理事长。湖中国康复医学会脊柱脊髓专业委员会微创脊柱外科学组委员。中国康复医学会骨与关节康复专业委员会脊柱三合联盟委员。中国医药教育协会骨科专业委员会脊柱分会委员。中国医药教育协会骨科专业委员会脊柱分会脊柱感染教育工作组委员。湖南省康复医学会脊柱脊髓专业委员会委员。湖南省康复医学会骨质疏松专业委员会委员。湖南省生物材料学会骨修复材料与器械专业委员会第一届委员。2013—2020年担任湘雅三医院骨科副主任。主持及承担各级科研项目10余项,其中主持湖南省科技厅3项、省自然科学基金2项。发表专业论文30余篇,主编和参编专著2部,曾在美国俄勒冈健康科技大学学习脊柱外科技术。李建,中南大学湘雅三医院助理研究员,2013年9月至2019年6月,在中南大学湘雅三医院获得临床检验诊断学硕士学位和博士学位,毕业后留院任职。以第一作者及通讯作者在国内外学术期刊上发表论文10余篇,申请国家发明专利3项,其中授权1项。研究工作主要围绕新型仿生纳米药物系统在肿瘤诊疗中的应用,阿尔茨海默病的免疫治疗等,主持包括国家自然科学基金青年项目、长沙市自然科学基金、中南大学研究生自主创新课题项目等。
引用本文:    
邬欣, 曾利胜, 王剑龙, 李建. 无机纳米颗粒在癌症治疗中的研究进展[J]. 材料导报, 2021, 35(Z1): 87-93.
WU Xin, ZENG lisheng, WANG Jianlong, LI Jian. Research Progress of Inorganic Nanoparticles in Cancer Therapy. Materials Reports, 2021, 35(Z1): 87-93.
链接本文:  
http://www.mater-rep.com/CN/  或          http://www.mater-rep.com/CN/Y2021/V35/IZ1/87
1 Molassiotis A, Cheng H L, Leung K T, et al.Brain and Behavior,2019,9(6),e01312.
2 Zhang J, Du Q, Song X, et al.Theranostics,2020,10(6),2621.
3 Bor G, Mat Azmi I D, Yaghmur A.Therapeutic Delivery,2019,10(2),113.
4 Ghilli M, Carretta E, Filippo F D, et al.European Journal of Cancer Care: the Official Journal of the European Oncology Nursing Society, 2017,26(4),51.
5 Bregoli L, Movia D, Gavigan-Imedio J D, et al.Nanomedicine : Nanotechnology, Biology, and Medicine,2016,12(1),81.
6 Lambert E, Gorantla V S, Janjic J M.Nanomedicine (London, England),2019,14(20),2697.
7 Xu M, Liu J, Xu X, et al.Materials (Basel, Switzerland),2018,11(10),81.
8 Li J, Huang X Y, Huang R, et al.CARBON,2019,132(146),660.
9 Heuer-Jungemann A, Feliu N, Bakaimi I, et al.Chemical Reviews,2019,119(8),4819.
10 Bayda S, Hadla M, Palazzolo S, et al.Current Medicinal Chemistry,2018,25(34),4269.
11 Bharti S, Kaur G, Jain S, et al.Journal of Drug Targeting,2019,27(8),813.
12 Vines J B, Yoon J H, Ryu N E, et al.Frontiers in Chemistry,2019,7(167),121.
13 Cherukula K, Manickavasagam Lekshmi K, Uthaman S, et al.Nanomaterials (Basel, Switzerland),2016,6(4),76.
14 Eom K, Byun K M, Jun S B, et al.Biophysical Journal,2018,115(8),1481.
15 Khunsuk P O, Chawalitpong S, Sawutdeechaikul P, et al.Molecular Pharmaceutics,2018,15(1),164.
16 Mayle K M, Dern K R, Wong V K, et al.SLAS Technology,2017,22(1),18.
17 Xu X, Chong Y, Liu X, et al.Acta Biomater,2019,56(84),328.
18 Loiseau A, Asila V, Boitel-Aullen G, et al.Biosensors,2019,9(2),78.
19 Verry C, Sancey L, Dufort S, et al.BMJ Open,2019,9(2),e023591.
20 US National Library of Medicine. ClinicalTrials.gov.[2019.01.28]https://clinicaltrials.gov/ct2/show/NCT03818386?term.
21 Verry C, Porcel E, Chargari C, et al.Cancer Radiother,2019,23(8),917.
22 Khalladi N and Thariat J.Bull Cancer,2019,106(12),1070.
23 Xie L, Jin W, Chen H, et al.J Biomed Nanotechnol,2019,15(2),215.
24 Carvalho S M, Leonel A G, Mansur A A P, et al.Biomater Sci,2019,7(5),2102.
25 Pang C, Brunelli A, Zhu C, et al.Nanotoxicology,2016,10(2),129.
26 Wilhelm S, Kaiser M, Wurth C, et al.Nanoscale,2015,7(4),1403.
27 Yang K, Wang C L, Ding S, et al. Material Reports,2019,33(5),1475.
28 Mahajan S, Patharkar A, Kuche K, et al. International Journal of Pharmaceutics,2018,548(1),540.
29 Yoo S, Hou J, Yi W, et al.Scientific Reports,2017,7(1),1071.
30 Li Y and Cao J.Science China. Life Sciences,2018,61(11),1333.
31 Mohajeri M, Behnam B and Sahebkar A.Journal of Cellular Physiology,2018,234(1),298.
32 Lin M S, Chen R T, Yu N Y, et al.Colloids and Surfaces B: Biointerfa-ces,2017,159,613.
33 Mauro N, Scialabba C, Agnello S, et al.Materials Science & Engineering: C, Materials for Biological Applications,2020,9(107),110201.
34 Tu Z, Wycisk V, Cheng C, et al.Nanoscale,2017,9(47) ,18931.
35 Lei W, Liu G, Zhang J, et al.Chemical Society Reviews,2017,46(12),3492.
36 Qin L, Jiang S, He H, et al.Journal of Controlled Release : Official Journal of the Controlled Release Society,2020,13(318),50.
37 Cheng C A, Deng T, Lin F C, et al.Theranostics,2019,9(11),3341.
38 Martinez-Carmona M, Lozano D, Colilla M, et al.Acta Biomater,2018,65,393.
39 Senapati S, Thakur R, Verma S P, et al.J Control Release,2016,53(224),186.
40 Zhang L X, Xie X X, Liu D Q, et al.Biomaterials,2018,13(174),54.
41 Mosquera J, García I and Liz-Marzán L M.Accounts of chemical Research,2018,51(9),2305.
42 Banerjee A, Qi J, Gogoi R, et al.Journal of controlled release : official Journal of the Controlled Release Society,2016,13(238),176.
43 Chen X, Tieleman D P and Liang Q.Nanoscale,2018,10(5),2481.
44 Sallem F, Boudon J, Heintz O, et al.Dalton Transactions (Cambridge, England : 2003),2017,46(44),15386.
45 Xia Q, Zhang Y, Li Z, et al.Acta pharmaceutica Sinica B,2019,9(4),675.
46 Hu C-M J, Fang R H, Wang K-C, et al.Nature,2015,526(7571),118.
47 Wu J, Chen J, Feng Y, et al. Journal of Gene Medicine,2019,21(7),e3088.
48 Mukherjee S, Liang L and Veiseh O.Pharmaceutics,2020,12(2),E147.
49 Hou C, Galvan D D, Meng G, et al.Physical Chemistry Chemical Ph-ysics,2017,19(35),24126.
50 Das P, Colombo M, Prosperi D.Colloids and Surfaces B: Biointerfaces,2019,35(174),42.
51 Ray Chowdhuri A, Bhattacharya D, Sahu S K.Dalton transactions (Cambridge, England : 2003),2016,45(7),2963.
52 Hervault A, Dunn A E, Lim M, et al.Nanoscale,2016,8(24),12152.
53 Libutti S K, Paciotti G F, Byrnes A A, et al.Clinical Cancer Research,2010,16(24),6139.
54 US National Library of Medicine. ClinicalTrials.gov.[2012.05.02]https://clinicaltrials.gov/ct2/show/NCT00436410?term.
55 Nanospectra Biosciences Company(2016).[2016-07-08].www.nanospectra.com.
56 US National Library of Medicine. ClinicalTrials.gov.[2012.05.02]https://clinicaltrials.gov/ct2/show/NCT00848024?term.
57 US National Library of Medicine. ClinicalTrials.gov.[2016.11.03]https://clinicaltrials.gov/ct2/show/NCT01679470?term.
58 Marill J, Anesary N M, Zhang P, et al.Radiat Oncol,2014,9,150,56-67.
59 US National Library of Medicine. ClinicalTrials.gov.[2018.06.04]https://clinicaltrials.gov/ct2/show/NCT02379845?term.
60 US National Library of Medicine. ClinicalTrials.gov.[2020.01.22]https://clinicaltrials.gov/ct2/show/NCT03589339?term.
61 US National Library of Medicine. ClinicalTrials.gov.[2018.06.04]https://clinicaltrials.gov/ct2/show/NCT02805894?term.
62 US National Library of Medicine. ClinicalTrials.gov.[2017.05.10]https://clinicaltrials.gov/ct2/show/NCT01433068?term.
63 US National Library of Medicine. ClinicalTrials.gov.[2020.01.03]https://clinicaltrials.gov/ct2/show/NCT02901483?term.
64 US National Library of Medicine. ClinicalTrials.gov.[2020.01.02]https://clinicaltrials.gov/ct2/show/NCT02465593?term.
65 US National Library of Medicine. ClinicalTrials.gov.[2017.02.03]https://clinicaltrials.gov/ct2/show/NCT02721056?term.
66 US National Library of Medicine. ClinicalTrials.gov.[2017.05.10]https://clinicaltrials.gov/ct2/show/NCT02033447?term.
67 Liu X, Zhang Y, Wang Y, et al.Theranostics,2020,10(8),3793.
68 Rivera Gil P, Huhn D, del Mercato L L, et al.Pharmacological Research,2010,62(2),115.
69 US National Library of Medicine.ClinicalTrials.gov.[2020.04.20https://clinicaltrials.gov/ct2/show/NCT04094077?term.
70 US National Library of Medicine.ClinicalTrials.gov.[2018.07.13https://clinicaltrials.gov/ct2/show/NCT03308604?term.
[1] 申欣, 孟昭旭, 廉鹤. 纳米羟基磷灰石复合材料在癌症治疗中的应用进展[J]. 材料导报, 2020, 34(Z2): 88-90.
[1] Huimin PAN,Jun FU,Qingxin ZHAO. Sulfate Attack Resistance of Concrete Subjected to Disturbance in Hardening Stage[J]. Materials Reports, 2018, 32(2): 282 -287 .
[2] Xu LI,Ziru WANG,Li YANG,Zhendong ZHANG,Youting ZHANG,Yifan DU. Synthesis and Performance of Magnetic Oil Absorption Material with Rice Chaff Support[J]. Materials Reports, 2018, 32(2): 219 -222 .
[3] WANG Tong, BAO Yan. Advances on Functional Polyacrylate/Inorganic Nanocomposite Latex for Leather Finishing[J]. Materials Reports, 2017, 31(1): 64 -71 .
[4] HUANG Dajian, MA Zonghong, MA Chenyang, WANG Xinwei. Preparation and Properties of Gelatin/Chitosan Composite Films Enhanced by Chitin Nanofiber[J]. Materials Reports, 2017, 31(8): 21 -24 .
[5] ZHANG Le, ZHOU Tianyuan, CHEN Hao, YANG Hao, ZHANG Qitu, SONG Bo, WONG Chingping. Advances in Transparent Nd∶YAG Laser Ceramics[J]. Materials Reports, 2017, 31(13): 41 -50 .
[6] CHEN Bida, GAN Guisheng, WU Yiping, OU Yanjie. Advances in Persistence Phosphors Activated by Blue-light[J]. Materials Reports, 2017, 31(21): 37 -45 .
[7] ZHANG Yong, WANG Xiongyu, YU Jing, CAO Weicheng,FENG Pengfa, JIAO Shengjie. Advances in Surface Modification of Molybdenum and Molybdenum Alloys at Elevated Temperature[J]. Materials Reports, 2017, 31(7): 83 -87 .
[8] JIN Chenxin, XU Guojun, LIU Liekai, YUE Zhihao, LI Xiaomin,TANG Hao, ZHOU Lang. Effects of Bulk Electrical Resistivity and Doping Type of Silicon on the Electrochemical Performance of Lithium-ion Batteries with Silicon/Graphite Anodes[J]. Materials Reports, 2017, 31(22): 10 -14 .
[9] FANG Sheng, HUANG Xuefeng, ZHANG Pengcheng, ZHOU Junpeng, GUO Nan. A Mechanism Study of Loess Reinforcing by Electricity-modified Sodium Silicate[J]. Materials Reports, 2017, 31(22): 135 -141 .
[10] ZHOU Dianwu, HE Rong, LIU Jinshui, PENG Ping. Effects of Ge, Si Addition on Energy and Electronic Structure of ZrO2 and Zr(Fe,Cr)2[J]. Materials Reports, 2017, 31(22): 146 -152 .
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed