Abstract: The tetracalcium phosphate (TTCP) doped with yttrium was prepared by high temperature solid state method. Then the TTCP doped with yttrium was mixed with dicalcium phosphate anhydrous (DCPA) at a molar ratio of 1∶1 to form ytt-rium-hydroxyapatite cement (Y-HAC). The results showed that the reaction product of Y-HAC is poorly crystalline hydroxyapatite, indicating that the addition of small amount of yttrium has not changed the hydration reaction of hydroxyapatite cement (HAC). The wet compressive strength of Y-HAC increased 120% and dry compressive strength increased 85%, compared with that of HAC. The porosity of specimens has been augmented with the doping of yttrium. There exists some changes in crystallization morphology of Y-HAC, emerging many closely combined flaked crystals and construct a three-dimensional network structure. The in-vitro release experiment indicated that Y-HACs have very low release of yttrium. The Y-HAC might be a potential material for bone substitute, drug-loaded and bone tissue engineering.
漆小鹏, 李文, 罗远方, 杨辉. 新型钇-羟基磷灰石骨水泥的制备及性能研究*[J]. CLDB, 2017, 31(13): 151-155.
QI Xiaopeng, LI Wen, LUO Yuanfang, YANG Hui. Preparation and Properties of a Novel Yttrium-hydroxyapatite Cement. Materials Reports, 2017, 31(13): 151-155.
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