Carboxyl-functionalized Carbon Nanotubes Reinforced Hybrid Supramolecular Hydrogel and Its Physical Properties
WANG Yuxiang1, FENG Chuanliang2
1 State Key Lab of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University,Shanghai 200240; 2 School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai 200240
Abstract: Hybrid supramolecular hydrogels embedded with carboxyl-functionalized carbon nanotubes (CNTs-COOH) were obtained via physical cross-linking. Transmission electron microscopy (TEM) were used to observe the microstructure of the sample. The effect of the introduction of the CNTs-COOH on the swelling behavior, gel-sol transition temperature and mechanical property of the gel were detected. The results revealed that compared with the initial gel, the inclusion of the carbon nanotubes(2.5wt.%)had no impacts on the morphology and microstructure of the gel, but caused an increase of its gel-sol transition temperature, also an ob-vious enhancement of the mechanical properties of the hybrid hydrogels. In addition, the hybrid hydrogel still retained the basic cha-racteristics of the supramolecular hydrogel, especially the characteristics of shear thinning, temperature sensitivity and spontaneous recovery.
1 Bennett S L, Melanson D A, Torchiana D F, et al. Next-generation hydrogel films as tissue sealants and adhesion barriers [J]. Card Surg,2003,18:494. 2 van Der Linden H, Herber S, Olthuis W, et al. Stimulus-sensitive hydrogels and their applications in chemical (micro)analysis [J]. Analyst,2003,128:325. 3 Drury J L, Mooney D J. Hydrogels for tissue engineering: Scaffold design vari-ables and applications [J]. Biomaterials,2003,24(24):4337. 4 Oh J K, Drumright R, Siegwart D J, et al. The development of microgeld/nanogels for drug delivery applications [J]. Prog Polym Sci,2008,33:448. 5 Tang Y Q, Heaysman C L, Willis S, et al. Physical hydrogel with self-assembled nanostructure as drug delivery systems [J]. Expert Opin Drug Delivery,2011,8:1141 6 Ma R, Xiong D, Miao F, et al. Novel PVP/PVA hydrogels for articular cartilage replacement [J]. Mater Sci Eng C,2009,29(6):1979. 7 Bodugoz-Senturk H, Macias C, Kung J, et al. Poly(vinyl alcohol)-acrylamide hydrogels as load-bearing cartilage substitute [J]. Biomaterials,2009,30(4):589. 8 Hyland L L, Taraban M B, Feng Y, et al. Viscoelastic properties and nanoscale structures of composite oligopeptide-polysaccharide hydrogels [J]. Biopolymers,2012,97:177. 9 Iijima S. Helical microtubules of graphitic carbon [J]. Nature,1991,354:56. 10 Treacy M, Ebbesen T, Gibson J. Exceptionally high Yong’s modulus observed for individual nanotubes[J]. Nature,1996,381:678. 11 Liu X W, Huang Y X, Sun X F, et al. Conductive carbon nanotube hydrogel as a bioanode for enhanced microbial electrocatalysis [J]. ACS Appl Mater Interfaces,2014,6:8158. 12 Giuseppe C, Silke H, Umile G S, et al. Carbon nanotubes hybrid hydrogels in drug delivery:A perspective review; review article [J]. Biomed Res Int,2014,2014:226. 13 Ruchir V M, Wu X, Jeremy S, et al. Nanotubes in biological applications[J]. Curr Opin Biotechnol,2014,28:25. 14 Kong H, Gao C, Yan D Y. Controlled functionalization of multiwalled carbon nanotubes by in situ atom transfer radical polymerization [J]. J Am Chem Soc,2004,126:412. 15 Edwards S, Werkmeister J, Ramshaw J. Carbon nanotubes in scaffolds for tissue engineering [J]. Expert Rev Med Devices,2009,6:499. 16 Saito N, Usui Y, Aoki K, et al. Carbon nanotubes: Biomaterial applications[J]. Chem Soc Rev,2009,38:1897. 17 Bryning M, Milkie D, Islam M, et al. Carbon nanotube aerogels[J]. Adv Mater,2007,19:661. 18 Ostojic G, Hersam M. Biomolecule-directed assembly of self-supported, nanoporous, conductive, and luminescent single-walled carbon nanotube scaffolds [J]. Small,2012,8:1840. 19 Cheng E, Li Y, Yang Z, et al. DNA-SWNT hybrid hydrogel [J]. Chem Commun,2011,47:5545. 20 Sheikholeslam M, Pritzker M, Chen P. Hybrid peptide-carbon nanotube dispersions and hydrogels [J]. Carbon,2014,71:284. 21 Shin S, Jung S, Zalabany M, et al. Carbon-nanotube-embedded hydrogel sheets for engineering cardiac constructs and bioactuators [J]. ACS Nano,2013,7:2369. 22 Chen Y S, Tsou P C, Jem M L, et al. Poly(N-isop ropylacrylamide) hydrogels with interpenetrating multiwalled carbon nanotubes for cell sheet engine erring [J]. Biomaterials,2013,34:7328. 23 Deep M, Tanmoy K, Prasanta K D. Pyrene-based fluorescent ambidextrous gelators:Scaffolds for mechanically robust SWNT-gel nanocomposites [J]. Chem Eur J,2014,20:1349. 24 Tomoki O, Yoshinori T, Hiroyasu Y, et al. Chemically-responsive sol-gel transition of supramolecular single-walled carbon nanotubes (swnts) hydrogel made by hybrids of swnts and cyclodextrins [J]. J Am Chem Soc,2007,129:4878. 25 Coleman J, Khan U, Blau W, et al. Small but strong: A review of the mechanical properties of carbon nanotube-polymer composites[J]. Carbon,2006,44(9):1624. 26 Liu L Q, Barber A, Nuriel S, et al. Mechanical properties of functionalized single-walled carbon-nanotube/poly(vinyl alcohol) nanocomposites [J]. Adv Funct Mater,2005,15(6):975. 27 Su R S, Hojae B, Jae M C, et al. Carbon nanotube reinforced hybrid microgels as scaff old materials for cell encapsulation [J]. ACS Nano,2012,6:362. 28 Ferris C, Panhuis M I H. Conducting bio-materials based on gellan gum hydrogels [J]. Soft Matter,2009,5:3430. 29 Miyako E, Nagata H, Hirano K, et al. Micropatterned carbon nanotube-gel composite as photothermal material [J].Adv Mater,2009,21:2819. 30 Miyako E, Nagata H, Hirano K, et al. Photodynamic thermoresponsive nanocarbon-polymer gel hybrids [J]. Small,2008,4:1711. 31 Fujigaya T, Morimoto T, Nakashima N. Isolated single-walled carbon nanotubes in a gel as a molecular reservoir and its application to controlled drug release triggered by near-IR laser irradiation [J]. Soft Matter,2011,7:2647. 32 Smart S, Cassady A, Lu G Q, et al. The biocompatibility of carbon nanotubes [J]. Carbon,2006,44(6):1034. 32 Pantarotto D, Briand J, Prato M, et al. Translocation of bioactive peptides across cell membranes by carbon nanotubes [J]. Chem Commun,2004,1:16. 34 Lu G, Moore J, Huang G, et al. RNA polymer translocation with single-walled carbon nanotubes [J]. Nano Lett,2004,4(12):2473. 35 Feng C L, Dou X Q, Zhang D, et al. A highly efficient self-assembly of responsive c2-cyclohexane-derived gelators [J]. Macromol Rapid Commun,2012,33:1535. 36 Huang R L, Qi W, Feng L B, et al. Self-assembling peptide-polysaccharide hybrid hydrogel as a potential carrier for drug delivery [J]. Soft Matter,2011,7:6222.
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2017, Vol. 31 
