Surface Modification of Collagen Films with Dopamine to Promote Cell Adhesion and Proliferation
CUI Guolian, DAN Nianhua, DAN Weihua
Key Laboratory of Leather Chemistry and EngineeringSichuan University,Ministry of Education;The Research Center of Biomedical Engineering and Technology, Sichuan University, Chengdu 610065;
Abstract: Dopamine has been widely used to surface modify materials due to its multi-functional reactivity and biocompatibility. Herein, in order to investigate whether the mechanical strength, hydrothermal stability, hydrophilic property and biocompatibility of collagen films are influenced, dopamine was used to surface-modify collagen films, and then the films were characterized. Results showed that the triple helix structure of collagen remains intact, and mechanical strength, hydrothermal stability and hydrophi-lic property of the films are enhanced. Besides, the films can promote adhesion and proliferation of fibroblasts.
崔国廉, 但年华, 但卫华. 多巴胺表面修饰胶原膜促进细胞粘附和增殖的研究*[J]. 《材料导报》期刊社, 2017, 31(2): 20-24.
CUI Guolian, DAN Nianhua, DAN Weihua. Surface Modification of Collagen Films with Dopamine to Promote Cell Adhesion and Proliferation. Materials Reports, 2017, 31(2): 20-24.
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2017, Vol. 31 
