A Review on the Modification and Application of Acellular Dermal Matrix
CHEN Yining1,2, DAN Weihua1,2, DAN Nianhua1,2
1 Key Laboratory of Leather Chemistry and Engineering of Ministry of Education, Sichuan University, Chengdu 610065; 2 National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065
Abstract: Acellular dermal matrix (ADM) is an aggregation of collagen fibers prepared by dermal tissue through a series of physical, chemical and biological processes, which displays low immunogenicity but relatively poor usability. And the physical and chemical properties of ADM can be improved by modification. This paper provide a vivid description over the research on the modification effect of ADM with respect to biological compatibility, stability and degradation resistance, mechanical properties, hydrophilicity, porosity, antibacterial ability and angiogenic properties, as well as a summary of the ADM’s immunologic properties, immunologic mechanisms, biological transition characteristics in tissue repair and clinical applications.
陈一宁, 但卫华, 但年华. 脱细胞真皮基质的改性及应用概述[J]. 《材料导报》期刊社, 2018, 32(13): 2311-2319.
CHEN Yining, DAN Weihua, DAN Nianhua. A Review on the Modification and Application of Acellular Dermal Matrix. Materials Reports, 2018, 32(13): 2311-2319.
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2018, Vol. 32 
