Please wait a minute...
材料导报  2020, Vol. 34 Issue (Z2): 327-329    
  金属与金属基复合材料 |
生物医用金属材料表面改性的研究进展
范燕, 徐昕荣, 石志峰, 刘佳, 李冰, 徐蒙蒙
华南理工大学医疗器械研究检验中心,广州 510006
Research Progress of Surface Modification of Biomedical Metallic Materials
FAN Yan, XU Xinrong, SHI Zhifeng, LIU Jia, LI Bing, XU Mengmeng
Medical Device Research and Testing Center, South China University of Technology, Guangzhou 510006, China
下载:  全 文 ( PDF ) ( 2082KB ) 
输出:  BibTeX | EndNote (RIS)      
摘要 与其他生物医用材料相比,生物医用金属材料具有更加优异的综合力学性能和加工成型能力,并且在骨植入器件、口腔医学和心血管疾病治疗医学等领域均得到了极其广泛的应用。由于生物医用金属材料需要在体液这种复杂的生理环境下进行服役,对其性能的要求十分严格。生物医用金属材料不仅需要在力学及其相关的物理性能方面满足要求,在抗生理腐蚀性能和生物相容性方面均需要表现出优异的特性。表面改性是指在保持材料或器件原性能的前提下赋予其表面新的性能,如耐腐蚀性及生物相容性等,是进一步提高医用金属材料表面性能的重要途径。本文根据材料的特点以及应用中存在的主要问题,综述了各类医用金属材料表面改性的研究现状,并对今后新型医用金属材料的发展方向进行了展望。
服务
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章
范燕
徐昕荣
石志峰
刘佳
李冰
徐蒙蒙
关键词:  生物医用金属材料  表面修饰  功能涂层  性能调控    
Abstract: Because of thebetter comprehensive mechanical properties and molding capacity than other biomedical materials, biomedical metal materials have been widely used in orthopedics, dentistry, cardiovascular disease treatment and other fields. Due to the working condition in such a complex physiological environment as body fluids, the requirements of biomedical metal materials are very strict. In addition to the mechanical and related physical properties, biomedical metal materials also should have excellent resistance to physiological corrosion and bio-compatibility. Surface modification technology, which can improve the performance of implanted devices and maintain the structural stability, has been widely used in various kinds of implanted devices. Based on the characteristics of the materials and the main problems in their application, this paper summarized the research status of surface modification of various kinds of medical metal materials, and prospected the development direction of new medical metal materials in the future.
Key words:  biomedical metallic materials    surface modification    functional coating    performance control
               出版日期:  2020-11-25      发布日期:  2021-01-08
ZTFLH:  TB31  
基金资助: 国家自然科学基金重点项目(U1609219);生物3D打印骨植入物的质量控制规范研究项目
通讯作者:  xxrong@scut.edu.cn   
作者简介:  范燕,2016年6月毕业于中国石油大学(北京),获得硕士学位。目前主要研究领域为表面改性及材料表征分析。徐昕荣,华南理工大学医疗器械研究检验中心高级工程师,长期从事生物材料与医疗器械的研究、分析表征及医疗器械监管科学研究。担任国家药品监督管理局医疗器械技术审评专家咨询委员会委员、全国外科植入物和矫形器械标准化技术委员会-骨科植入物分技术委员会委员和全国口腔材料和器械设备标准化技术委员会委员。
引用本文:    
范燕, 徐昕荣, 石志峰, 刘佳, 李冰, 徐蒙蒙. 生物医用金属材料表面改性的研究进展[J]. 材料导报, 2020, 34(Z2): 327-329.
FAN Yan, XU Xinrong, SHI Zhifeng, LIU Jia, LI Bing, XU Mengmeng. Research Progress of Surface Modification of Biomedical Metallic Materials. Materials Reports, 2020, 34(Z2): 327-329.
链接本文:  
http://www.mater-rep.com/CN/  或          http://www.mater-rep.com/CN/Y2020/V34/IZ2/327
1 Zheng Y F, Wu Y H. Acta Metallurgica Sinica, 2017, 53(3), 257 (in Chinese).
郑玉峰,吴远浩.金属学报, 2017, 53(3), 257.
2 Sezer N, Evis Z, Kayhan S M, et al. Journal of Magnesium and Alloys, 2018, 6, 23.
3 Li L Y, Cui L Y, Zeng R C, et al. Acta Biomaterialia, 2018, 79, 23.
4 张文毓.金属世界, 2020(1), 21.
5 Mahajan A, Sidhu S S. Materials Technology, 2017, 33(2), 93.
6 Wan P, Tan L, Yang K. Journal of Materials Science & Technology, 2016, 32(9), 827.
7 Ma X, Zhu S J, Wang L G, et al. Journal of Alloys and Compounds, 2014, 590, 247.
8 Xu R Z, Shen Y, Zheng J, et al. Surface and Coatings Technology, 2017, 309, 490.
9 方信贤,章晓波,王强,等.中国有色金属学报, 2014, 24(5), 1285.
10 薛顺. 电泳沉积镁合金基羟基磷灰石涂层研究. 硕士学位论文, 南华大学,2015.
11 Chen L J, Zhao J, Yu K, et al. Rare Metal Materials and Engineering, 2015, 44(8), 1862.
12 杨柯.中国医疗设备,2015,30(9), 1674.
13 赵杰,郭磊,付玉平,等.稀有金属材料与工程, 2013, 5,1013.
14 Geng F, Tan L, Zhang B, et al. Journal of Materials Science & Technology, 2009, 25(1), 123.
15 Ren L, Lin X, Tan L, et al. Materials Letters, 2011, 65, 3509.
16 邹玉红,王建,曾荣昌,等. 中国专利,CN107227453A, 2017-10-03.
17 林潇,任玲,杨柯. 中国专利,CN104645422A, 2015-05-27.
18 王伟. 医用Mg-Zn-Zr-Sr合金表面水滑石及其抗菌涂层研究.硕士学位论文, 天津理工大学,2018.
19 陈亚芍,杜敏婷,李玉环,等.中国专利,CN107789664A, 2018-03-13.
20 杨淑野. 钴铬合金颗粒及其金属离子Co2+,Cr3+导致的关节假体松动的基础研究.硕士学位论文, 山东大学,2015.
21 李亚兰,肖华. 中国专利, CN102990069A, 2013-03-27.
22 李春晓,杨杰书,张静静. 中国专利,CN108186175A, 2018-06-22.
23 徐林.低温等离子体氮化医用316L不锈钢和CoCrMo合金表面的性能及机理研究. 硕士学位论文,东北大学,2016.
24 陈威.镍铬钴合金高温耐磨涂层制备工艺及其性能研究.硕士学位论文,山东大学,2012.
25 姜丽.镀金对支架用钴铬合金表面微生物黏附的影响.硕士学位论文,山东大学,2012.
26 于普良,杜辉,李双,等.材料导报, 2018, 32(专辑32), 303.
27 杨莉.CoCrMo合金沉积DLC膜的摩擦学性能及金属离子释放研究.硕士学位论文,中国矿业大学,2014.
28 任军帅,张英明,谭江,等.材料导报, 2016, 30(专辑28),384.
29 郭二彬.激光冲击微造型提高医用钛合金Ti13Nb13Zr耐磨性能研究.硕士学位论文,江苏科技大学,2017.
30 Hang R, Qi Y.Diamond and Related Materials, 2010, 19(1), 62.
31 任冰,万熠,王桂森,等. 表面技术, 2018, 47(4),160.
32 金旭丹,杨晓康,魏芬绒,等.世界有色金属, 2018, 33(7), 153.
33 Meng F H, Li Z H, Liu X Y. Surface & Coatings Technology, 2013, 229, 205.
34 卿云安.医用钛合金表面TaN-Ag复合涂层抗菌性能的研究.硕士学位论文,吉林大学,2019.
35 李满.医用钛合金表面抗菌与生物活性双功能杂化涂层的构建.硕士学位论文, 湖北大学, 2016.
36 Van't Hof W, Veerman E C I, Helmerhorst E J, et al. Biological Chemistry, 2001, 382(4), 597.
37 尹玉霞,王鲁宁,郝树斌,等.中国医疗设备,2019,34(6),153.
38 Wang H F, Tang B, et al. Materials Science and Technology, 2011, 27(4),309.
39 Dan Z G, Ni H W. Thin Solid Films,2005,492,93.
40 高晓晋.Cu离子注入A304不锈钢抗菌性能研究.硕士学位论文, 昆明理工大学,2009.
41 Ni H W, Zhang H S, Chen R S. International Journal of Minerals Metallurgy and Materials, 2012, 19(4), 322.
42 Panicaud B, Retraint D, Grosseau-Poussard J L,et al. Corrosion Science, 2012, 60, 224.
43 钟祥玉,李谋成,姚美意,等.上海金属, 2010(1), 34.
44 Kim H G, Jeong Y H, Kim T H. Journal of Nuclear Materials, 2004, 326 (2-3), 125.
45 周林菊.医用锆铌合金氧化陶瓷层的制备及其性能研究.硕士学位论文, 华南理工大学,2015.
46 许亚雄. 中国专利, CN110469072A, 2019-11-19.
47 刘玉玲,张修庆.材料导报, 2019, 33(专辑34), 331.
48 Shen C, Liu X W, Fan B, et al. RSC Advances, 2016, 89,85675.
[1] 吴成宝, 林列书, 李慎兰, 盖国胜, 杨玉芬. 表面纳米修饰重质碳酸钙的制备及形貌特征和粒度表征[J]. 材料导报, 2019, 33(z1): 149-152.
[2] 张燕. 一步法制备无表面修饰剂花状金纳米颗粒及其表面增强拉曼散射性能研究[J]. 材料导报, 2019, 33(z1): 314-317.
[3] 赵晓光, 欧阳静, 张毅, 杨华明. 矿物基摩擦材料的研究进展[J]. 材料导报, 2019, 33(11): 1860-1868.
[4] 白静静, 苏会博, 刘志伟. 异氰酸酯功能化碳纳米管/热塑性聚氨酯弹性体复合材料的制备及流变性能[J]. 材料导报, 2018, 32(24): 4386-4391.
[5] 徐亦冬, 曾鞠庆, 陈伟, 毛江鸿, 沈建生, 胡丹烨. 氧化石墨烯增强水泥基复合材料的研究现状及展望*[J]. 《材料导报》期刊社, 2017, 31(23): 150-155.
[6] 崔国廉, 但年华, 但卫华. 多巴胺表面修饰胶原膜促进细胞粘附和增殖的研究*[J]. 《材料导报》期刊社, 2017, 31(2): 20-24.
[7] 张研, 刘康恺, 孟龙月. 荧光碳量子点的制备及其在生物医用领域的研究进展*[J]. 《材料导报》期刊社, 2017, 31(15): 126-132.
[1] Ninghui LIANG,Peng YANG,Xinrong LIU,Yang ZHONG,Zheqi GUO. A Study on Dynamic Compressive Mechanical Properties of Multi-size Polypropylene Fiber Concrete Under High Strain Rate[J]. Materials Reports, 2018, 32(2): 288 -294 .
[2] WANG Tong, BAO Yan. Advances on Functional Polyacrylate/Inorganic Nanocomposite Latex for Leather Finishing[J]. Materials Reports, 2017, 31(1): 64 -71 .
[3] GUO Hongjian, JIA Junhong, ZHANG Zhenyu, LIANG Bunu, CHEN Wenyuan, LI Bo, WANG Jianyi. Microstructure and Tribological Properties of VN/Ag Films Fabricated by Pulsed Laser Deposition Technique[J]. Materials Reports, 2017, 31(2): 55 -59 .
[4] WANG Wenjin, WANG Keqiang, YE Shenjie, MIAO Weijun, CHEN Zhongren. Effect of Asymmetric Block Copolymer of PI-b-PB on Phase Morphology and Properties of IR/BR Blends[J]. Materials Reports, 2017, 31(2): 96 -100 .
[5] HUANG Dajian, MA Zonghong, MA Chenyang, WANG Xinwei. Preparation and Properties of Gelatin/Chitosan Composite Films Enhanced by Chitin Nanofiber[J]. Materials Reports, 2017, 31(8): 21 -24 .
[6] YUAN Xinjian, LI Ci, WANG Haodong, LIANG Xuebo, ZENG Dingding, XIE Chaojie. Effects of Micro-alloying of Chromium and Vanadium on Microstructure and Mechanical Properties of High Carbon Steel[J]. Materials Reports, 2017, 31(8): 76 -81 .
[7] ZHANG Le, ZHOU Tianyuan, CHEN Hao, YANG Hao, ZHANG Qitu, SONG Bo, WONG Chingping. Advances in Transparent Nd∶YAG Laser Ceramics[J]. Materials Reports, 2017, 31(13): 41 -50 .
[8] YAN Zhilong, LI Yongsheng, HU Kai, ZHOU Xiaorong. Progress of Study on Phase Decomposition of Duplex Stainless Steel[J]. Materials Reports, 2017, 31(15): 75 -80 .
[9] SHI Yu, ZHOU Xianglong, ZHU Ming, GU Yufen, FAN Ding. Effect of Filler Wires on Brazing Interface Microstructure and Mechanical Properties of Al/Cu Dissimilar Metals Welding-Brazing Joint[J]. Materials Reports, 2017, 31(10): 61 .
[10] DONG Fei,YI Youping,HUANG Shiquan,ZHANG Yuxun,. TTT Curves and Quench Sensitivity of 2A14 Aluminum Alloy[J]. Materials Reports, 2017, 31(10): 77 -81 .
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed