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材料导报  2019, Vol. 33 Issue (z1): 408-411    
  金属与金属基复合材料 |
金属有机骨架材料在生物样品前处理中的应用进展
傅寅旭, 许雨熙, 诸葛黔, 王磊, 宋煦, 王旭
杭州医学院检验医学院,杭州 310053
Application of Metal-organic Frameworks in Biological Sample Pretreatment
FU Yinxu, XU Yuxi, ZHUGE Qian, WANG Lei, SONG Xu, WANG Xu
College of Laboratory Medicine,Hangzhou Medical College, Hangzhou 310053
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摘要 样品前处理是生物样品分析过程中的重要一环,为了去除基质的干扰、富集微量待测物质,通常需要进行合适、高效的前处理。金属有机骨架(MOFs)由金属离子和有机配体构成,是近年来涌现出的一类新型多功能多孔晶体材料,因具有比表面积高、孔隙率大、热稳定性好和功能多样化等特点,在分析化学领域备受关注。主要概述了MOFs的制备方法,总结了MOFs作为新型吸附剂在生物样品前处理中的应用。此外,还探讨了MOFs在生物样品前处理过程中的不足和发展前景。
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傅寅旭
许雨熙
诸葛黔
王磊
宋煦
王旭
关键词:  金属有机骨架材料  多孔晶体  生物样品  前处理    
Abstract: Sample pretreatment is an important part of the biological sample analysis process. In order to remove the interference of matrix and enrich trace substances to be tested, appropriate and efficient pretreatment is usually required. Metal-organic frameworks (MOFs), composed of metal ions and organic ligands, is a new type of multi-functional porous crystal material emerging in recent years. It has been attracted in the field of analytical chemistry due to its high specific surface area, large porosity, good thermal stability and diverse functions. This review mainly summarizes the preparation methods of MOFs, summarizes the application of MOFs as a new adsorbent in the pretreatment of biological samples, and also discusses the shortcomings and development prospects of MOFs in the pretreatment of biological samples.
Key words:  metal-organic frameworks(MOFs)    porous crystal    biological sample    pretreatment
               出版日期:  2019-05-25      发布日期:  2019-07-05
ZTFLH:  O652.6  
  R318  
基金资助: 2019年杭州医学院大学生创新创业训练计划项目
作者简介:  傅寅旭,2016年9月至今,就读于杭州医学院。申请国家发明专利1项,授权国家实用新型发明专利1项。全国大学生生命科学竞赛三等奖,浙江省大学生生命科学竞赛一等奖,国家大学生创新创业项目2项,在王旭教授的指导下进行研究。目前主要研究领域为磁性纳米材料在检验医学领域的应用。王旭,博士,杭州医学院教授,浙江省高校中青年学科带头人。2007年6月毕业于浙江大学化学系,获得理学博士学位。 主要研究方向:卫生检验学和生物热力学。近年主持国家级项目一项,省部级项目两项,以第一或者通讯作者发表SCI论文十余篇,授权发明专利一项,获得分析测试协会科学技术奖三等奖一项。wangxu@hmc.edu.cn
引用本文:    
傅寅旭, 许雨熙, 诸葛黔, 王磊, 宋煦, 王旭. 金属有机骨架材料在生物样品前处理中的应用进展[J]. 材料导报, 2019, 33(z1): 408-411.
FU Yinxu, XU Yuxi, ZHUGE Qian, WANG Lei, SONG Xu, WANG Xu. Application of Metal-organic Frameworks in Biological Sample Pretreatment. Materials Reports, 2019, 33(z1): 408-411.
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http://www.mater-rep.com/CN/  或          http://www.mater-rep.com/CN/Y2019/V33/Iz1/408
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