Materials Reports 2021, Vol. 35 Issue (z2): 492-500 |
POLYMERS AND POLYMER MATRIX COMPOSITES |
|
|
|
|
|
Application of Shape Memory Polymer Smart Materials in Biomedical Field |
WU Xuelian1, YANG Jian1, QU Yang2, WANG Xiumin3
|
1 School of Mechanical Engineering, Jiangsu University, Zhenjiang 212013, China 2 School of Pharmacy, Jiangsu University, Zhenjiang 212013, China 3 School of Science, Beijing University of Civil Engineering and Architecture, Beijing 100044, China |
|
|
Abstract In recent years, shape memory polymers (SMP), as a new type of smart materials, have shown a very bright potential application prospect in the field of biomedicine. Compared with traditional metal medical devices, the application of SMP in biomedical field has the following three characteristics: (Ⅰ) the adaptive characteristic can be achieved by mean of that shape memory effect; (Ⅱ) Better biocompatibility with human body, and adjustable biodegradability; (Ⅲ) the mechanical property can be adjusted and controlled in a wide range, and the matching property with human tissues is better. In this paper, the applications of SMP smart materials in the biomedical field are summarized, and the applications in the fields of medical devices, bones, drug delivery and bioelectronic medicine are introduced respectively. The existing problems were analyzed and the prospects were prospected, in order to provide a useful reference for the application of shape memory polymers in the field of biomedical engineering.
|
Published: 09 December 2021
|
|
About author:: Xuelian Wu received her Ph.D. edgree in Institute of Composite Materials and Structure, School of Astronautics, Harbin Institute of Technology, in 2011. She is currrently associate in School of Mechanical Enginee-ring, Jiangsu University. Her research interests are preparation, characterization ang engineering application of functional polymers ang their composities. Jian Yang received his B.E. degree in mechanical design manufacture and automation from Jilin Institute of Chemical Technology in 2019. He is currently pursuing his M.S. at the School of Mechanical Engineering, Jiangsu University of Prof. Xuelian Wu. His research has focused on conductive functionalization ang biological properties of shape memory polymer. |
|
|
1 李涤尘, 刘佳煜, 王延杰, 等. 机电工程技术, 2014, 43(5), 1. 2 冷劲松, 孙健, 刘彦菊. 航空学报, 2014, 35(1), 29. 3 刘俊聪, 王丹勇, 李树虎, 等. 航空制造技术, 2014(Z1), 130. 4 杨正岩, 张佳奇, 高东岳, 等.航空制造技术, 2017(17), 36. 5 鄢健宇, 王勇越, 李培培.技术与市场, 2017, 24(5), 198. 6 Behl M, Lendlein A. Materials Today, 2007, 10, 20. 7 Xiao R, Huang W M. Macromol Bioscience, 2020, 20, e2000108. 8 Yi L, Liu J. International Materials Reviews, 2017, 62, 415. 9 Yang J, Guo J L, Mikos A G, et al. Annals of Biomedical Engineering, 2018, 46, 1229. 10 Yang J, Yang Y W. Small, 2020, 16, e1906846. 11 张文毓. 金属世界, 2020(1),21. 12 Makvandi P, Wang C Y, Zare E N, et al. Advanced Functional Mate-rials, 2020, 30, 1910021. 13 施娟娟.当代化工研究, 2020(14),80. 14 Li Y, Zhang F, Liu Y, et al. Science China Technological Sciences, 2020, 63, 545. 15 朱文超,崔海坡,郭丹一, 等. 中国组织工程研究, 2014, 18(47), 7677. 16 Chan B Q, Low Z W, Heng S J, et al. ACS Applied Materials Interfaces, 2016, 8, 10070. 17 Ze Q, Kuang X, Wu S, et al. Advanced Materials, 2020, 32, e1906657. 18 Zhao W, Zhang F, Leng J, et al. Composites Science and Technology, 2019, 184, 1506. 19 Gu S Y, Chang K, Jin S P. Journal of Applied Polymer Science, 2018, 135, 45686. 20 Herting S M, Ding Y, Boyle A J, et al. Journal Biomedical Materials Research part B:Applied Biomaterials, 2019, 107, 2466. 21 Wong Y S, Salvekar A V, Zhuang K D, et al. Biomaterials, 2016, 102, 98. 22 Gong T, Zhao K, Liu X, et al. Small, 2016, 12, 5769. 23 Lendlein A. Science, 2002, 296(5573),1673. 24 Lee H S, Park S H, Lee J H, et al. Materials Letters, 2013, 95, 40. 25 Peng X, Liu G, Zhu L, et al. Carbohydrate Research, 2020, 496, 108115. 26 Zhou W C, Tan P F, Chen X H, et al. Frontiers in Pharmacology, 2019, 10, 1506. 27 Zhang D, George O J, Petersen K M, et al. Acta Biomaterialia, 2014, 10, 4597. 28 Xie R, Hu J, Hoffmann O, et al. Biochimica et Biophysica Acta General Subjects, 2018, 1862, 936. 29 Yu J, Xia H, Ni Q Q. Journal of Materials Science, 2017, 53, 4734. 30 全皓月,聚己内酯基形状记忆复合材料及骨外固定器的制备与性能研究. 硕士学位论文, 哈尔滨工业大学, 2020. 31 赵伟,基于形状记忆聚合物的自适应骨折固定装置研究. 硕士学位论文, 哈尔滨工业大学, 2016. 32 Zhu W, Huang W, Ye L, et al. Chemical Engineering Science, 2020, 228, 115981. 33 Fang Z, Kuang Y, Zhou P, et al. ACS Applied Materials & Interfaces, 2017, 9, 5495. 34 Wang L, Wu Y, Hu T, et al. Acta Biomaterials, 2017, 59, 68. 35 Xu X, Fan P, Ren J, et al. Composites Science and Technology, 2018, 168, 255. 36 Yan H, Li L, Shi X, et al. Polymer Testing, 2020, 90, 106672. 37 Kai D, Tan M J, Prabhakaran M P, et al. Colloids and Surfaces B: Biointerfaces, 2016, 148, 557. 38 Zhao X, Guo B, Wu H, et al. Nature Communications, 2018, 9, 2784. 39 赵建宝, 吴雪莲, 戈晓岚, 等. 材料导报:综述篇, 2015, 29(11),75. |
|
|
|