智能印迹聚合物研究进展及发展瓶颈

doi:10.11896/cldb.19070026

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Abstract Some intrinsic advantages, such as structural predetermination, long-term stability, wide applicability, specific recognition, added to the superiority of cost and preparation technology, make imprinted polymers (IPs) displaying potential application prospect in separation science, solid phase extraction, chromatographic separation, drug controlled release, chemical sensing, environmental detection, electrochemistry, membrane separation and many other fields, which, in fact, provide a foundation material basis and technical support for the accurate separation of templates. Nowadays, with the concept of sustainable development and circular economy accepted increasingly. IPs will be focused more as a research hotspot in the field of high performance functional materials inevitably.
However, IPs prepared by the traditional method is a highly cross-linked polymer, and the high cross-linking degree endowing IPs advantages of stable structure and strong recognition. However, owing to the simple and mechanical molecular recognition mechanism resulted from high cross-linking degree, IPs prepared by traditional method lacked the necessary "flexibility" and sufficient sensitivity to external stimulation conditions, which resulted in the difficulty to balance the desorption rate, selectivity and reusability during the separation and purification process, and further limited them application in practical industrial separation. In recent years, researchers' interest has gradually shifted to smart imprinted polymers that can improve the “flexibility” of traditional IPs.
A new type of functional material, namely smart imprinted polymers (S-IPs), was prepared by combining smart polymers (SPs) with imprinted polymers (IPs). It not only has the specific selectivity of common imprinted polymers, but also has the characteristics of responsiveness to external stimuli and reversibility of deformation, which makes them more excellent in adsorption and desorption. Research on S-IPs had achieved series of exciting results. Studies had successfully prepared temperature-sensitive IPs (T-IPs), magnetically responsive IPs (M-IPs), pH-sensitive IPs (pH-IPs), photoresponsive IPs (P-IPs) and dual-sensitive IPs (pH-M IPs, pH-T IPs, TM IPs, PM IPs, etc.) and multiple-sensitivity S-IPs, and all above had presented strong prospects in areas such as drug delivery, biotechnology, separation science and sensor etc.
This paper mainly reviews the research progress of S-IPs in intelligent mechanism and preparation method. Finally, key bottlenecks that hold back the development of S-IPs are summarizes, and the potential development prospect is concerned.

Key words： smart imprinted polymers mechanism of action preparation methods development bottleneck

Published: 14 July 2020

CLC number:

TQ32

Fund:This work was financially supported by the Joint Fund between Shenyang National Laboratory for Materials Science and State Key Laboratory of Advanced Pro-cessing and Recycling of Nonferrous Metals (18LHZD003, 18LHPY004).

About author:: Xiaoyan Zhang is currently pursuing her a master's degree at the Institute of Materials, Lanzhou University of Technology, under the supervision of Prof. Zhenbin Chen. Her research has focused on the preparation of ruthenium ion imprinted polymer and its adsorption separation performance.
Zhenbin Chen, is a Professor of Materials Science at Lanzhou University of Technology. He obtained his Ph.D. degree at Lanzhou University from 2002 to 2007, and has taught at the School of Materials Science and Technology of Lanzhou University of Technology since 2007. During the year 2008—2011, he worked as a postdoctoral researcher at Lanzhou Compound of the Chinese Academy of Sciences. He has been engaged in the research of adsorption-separating functional polymer materials for a long time. He has completed one project of Gansu Natural Science Foundation and one funded master's tutor fund project of Gansu Provincial Education Department. He is a technical person in charge of the National Natural Science Foundation of China and two higher education institutions in
Gansu Province. Zhenbin, has 1 basic research fund, 1 teaching achievement award from Gansu Provincial Education Department, and 2 patent applications. Published more than 50 papers, including 32 articles in SCI and EI. In 2012, the company won the third prize of the “Kaihuaneng Cup”, the third national college student energy conservation and emission reduction social practice and science and technology competition, the “Instructor Award”, the Lanzhou University of Technology graduation thesis-“Excellent Instructor”, and the “Excellent Instructor” award of the Lanzhou University of Technology Student Business Plan Competition. He participated in the “polymer physics” national courseware production competition in 2013, which won the third price of the competition.

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Cite this article:

ZHANG Xiaoyan,SUN Yuan,LI Hui, et al. Research Progress and Development Bottleneck of the Smart Imprinted Polymer[J]. Materials Reports, 2020, 34(15): 15163-15173.

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http://www.mater-rep.com/EN/10.11896/cldb.19070026 OR http://www.mater-rep.com/EN/Y2020/V34/I15/15163

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