氧化铱/聚多巴胺/层粘连蛋白仿生涂层的制备

doi:10.11896/j.issn.1005-023X.2018.24.026

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Abstract The biocompatibility of electrode-tissue interface is a crucial factor that influences the long-term performances of neural prosthesis. The modification of the electrode surface can significantly improve the biocompatibility at the implant site. Iridium oxide films were formed on the surface of titanium substrate by RF magnetron sputtering and cyclic voltammetry. Modified by dopamine and laminin, the iridium oxide/polydopamine/laminin biomimetic layer was prepared. The physical and chemical characterizations of the biomimetic layer show that the electrochemical properties and hydrophilicity are significantly improved. The layer is stable, without cytotoxicity. Besides, the layer promotes cell adhesion of PC12.

Key words： iridium oxide dopamine biomimetic layer biocompatibility

Published: 23 January 2019

CLC number:

TB333

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	Articles by authors
	RUAN Shichao
	LUO Dandan
	HAO Ya
	BAI Xue
	CHEN Cen

Cite this article:

RUAN Shichao,LUO Dandan,HAO Ya, et al. Preparation of Iridium Oxide/Polydopamine/Laminin Biomimetic Layer[J]. Materials Reports, 2018, 32(24): 4351-4356.

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http://www.mater-rep.com/EN/10.11896/j.issn.1005-023X.2018.24.026 OR http://www.mater-rep.com/EN/Y2018/V32/I24/4351

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