季铵化壳聚糖改性ZnO/凹凸棒石纳米复合材料及其抗菌性能

doi:10.11896/cldb.21110131

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Abstract One-dimensional nanorods of attapulgite (APT) have broad applications prospects in functional carriers. In this work, APT as a carrier to load ZnO nanoparticles, and quaternized chitosan was used to modify the surface charge of ZnO/APT nanocomposites to enhance antibacterial activity. The structure analysis of ZnO/APT nanocomposites were characterized by XRD, FESEM, TEM, EDS and BET, the quaterni-zed chitosan modified ZnO/APT were characterized by FTIR and Zeta potential. The results indicated that ZnO nanoparticles were evenly loaded on the surface of APT, and also the nanocomposites were successfully modified by quaternized chitosan. The minimum inhibitory concentration (MIC) results indicated that 5% quaternized chitosan modified ZnO/APT nanocomposites were 0.25 mg/mL for Staphylococcus aureus and 0.5 mg/mL for Escherichia coli, respectively. Meanwhile, the cytotoxicity test showed that the survival rate of quaternized chitosan modified ZnO/APT to HeLa cells was more than 97.3%, which displayed good biocompatibility.

Key words： quaternary ammonium chitosan ZnO attapulgite antibacterial activity

Published: Online: 2022-02-10

CLC number:	TB34
	TB332

Fund:Regional Key Project of the Science and Technology Service of the Chinese Academy of Sciences (KFJ-STS-QYZX-086) and the Major Projects of the Natural Science Foundation of Gansu, China (18JR4RA001).

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	Articles by authors
	HUI Aiping
	MA Mengting
	YANG Fangfang
	KANG Yuru
	WANG Aiqin

Cite this article:

HUI Aiping,MA Mengting,YANG Fangfang, et al. Antibacterial Activity of Quaternized Chitosan Modified ZnO/Attapulgite Nanocomposites[J]. Materials Reports, 2022, 36(3): 21110131-7.

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http://www.mater-rep.com/EN/10.11896/cldb.21110131 OR http://www.mater-rep.com/EN/Y2022/V36/I3/21110131

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