Please wait a minute...
材料导报  2025, Vol. 39 Issue (14): 24060199-9    https://doi.org/10.11896/cldb.24060199
  无机非金属及其复合材料 |
医用手术电极抗粘连材料的研究进展
唐同, 宓保森, 马迅, 王静静, 陈天驹, 刘平, 李伟*
上海理工大学材料与化学学院,上海 200093
Research Progress of Anti-adhesion Materials for Medical Electrodes
TANG Tong, MI Baosen, MA Xun, WANG Jingjing, CHEN Tianju, LIU Ping, LI Wei*
School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China
下载:  全 文 ( PDF ) ( 34244KB ) 
输出:  BibTeX | EndNote (RIS)      
摘要 电外科手术器械(高频电刀、离子刀等)是实现微创手术的一种重要器械,具有切割速度快、渗血少等诸多优点。然而,在使用过程中电极表面会产生高温导致血液和组织中的体液汽化,造成血液和软组织粘附,形成焦痂,从而严重影响手术的效果。医用手术电极抗粘连材料凭借其独特的抗组织粘附、疏血和抑菌等功能,在外科和微创手术等医疗领域展现出重要的研究和应用价值。本文对医用手术电极抗粘连材料的研究进展进行了系统综述。首先,分析了电极表面粘附行为及粘附机制。其次,总结了医用电极实现抗粘连性能的方法,重点介绍了当前医用手术电极表面涂覆抗粘连涂层、设计电极表面微观结构以及使用具有抗粘连性能的材料这三种方法的研究进展。通过对现有研究的分析,深入探讨了各方法的基本原理和技术进展。最后,针对医用电极抗粘连材料的发展现状和存在的问题进行分析并提出了展望,为后续医用抗粘连材料的研究提供借鉴和指导。
服务
把本文推荐给朋友
加入引用管理器
E-mail Alert
RSS
作者相关文章
唐同
宓保森
马迅
王静静
陈天驹
刘平
李伟
关键词:  抗粘连材料  医用手术电极  电外科手术器械  抗组织粘附    
Abstract: Electrosurgical surgical instruments such as high-frequency electric knife, ion knife, etc. are an important kind of instrument for minimally invasive surgery, with many advantages such as fast cutting speed and less bleeding. However, high temperature generated on the surface of the electrode during use will lead to the vaporization of body fluids in blood and tissue, resulting in adhesion of blood and soft tissue and formation of eschar, which seriously affects the effect of surgery. The anti-adhesion material for medical surgical electrode has shown important research and application value in medical fields such as surgery and minimally invasive surgery due to its unique functions of anti-tissue adhesion, bleeding and bacteriostasis. In this summary, the research progress of anti-adhesion materials for medical surgical electrodes is systematically reviewed. Firstly, based on the theoretical basis of solid interface bonding, the adhesion behavior and adhesion mechanism of electrode surface are analyzed. Secondly, the methods of achieving anti-adhesion performance of medical electrodes are summarized, among these, there main methods' research progress are introduced, which are coating anti-adhesion meterials on the surface of medical surgical electrodes, designing the microstructure of electrode surface and using materials with anti-adhesion properties. Through the analysis of the existing research, the basic principles and technical progress of each method are discussed in depth. Finally, the development status and existing problems of medical electrode anti-adhesion materials are analyzed and prospected, which is expected to provides reference and guidance for the subsequent research of medical anti-adhesion materials.
Key words:  anti-adhesion material    medical surgical electrode    electrical surgical instruments    anti-tissue adhesion
出版日期:  2025-07-25      发布日期:  2025-07-29
ZTFLH:  O647.4  
  R616.1  
基金资助: 国家自然科学基金(51971148); 上海市地方高校能力建设项目(22010503000); 上海高性能医疗器械材料工程技术研究中心(20DZ2255500)
通讯作者:  * 李伟,上海理工大学材料与化学学院教授、博士研究生导师。从事纳米结构功能薄膜材料、生物医用材料、高熵合金材料、PVD技术及其应用方面的研究。liwei176@usst.edu.cn   
作者简介:  唐同,上海理工大学材料与化学学院硕士研究生,在李伟教授的指导下进行研究。目前主要从事医用金属基抗粘连材料领域的研究。
引用本文:    
唐同, 宓保森, 马迅, 王静静, 陈天驹, 刘平, 李伟. 医用手术电极抗粘连材料的研究进展[J]. 材料导报, 2025, 39(14): 24060199-9.
TANG Tong, MI Baosen, MA Xun, WANG Jingjing, CHEN Tianju, LIU Ping, LI Wei. Research Progress of Anti-adhesion Materials for Medical Electrodes. Materials Reports, 2025, 39(14): 24060199-9.
链接本文:  
https://www.mater-rep.com/CN/10.11896/cldb.24060199  或          https://www.mater-rep.com/CN/Y2025/V39/I14/24060199
1 Shin N, Ozaki A, Tanimoto T. JAMA Surgery, 2023, 158, 775.
2 Song Z, Wang G, Zhu L, et al. Journal of Central South University(Medical Science), 2023, 48(2), 221 (in Chinese).
宋智, 王国慧, 朱利勇, 等. 中南大学学报(医学版), 2023, 48(2), 221.
3 Su H, Bu Z D. Chinese Journal of Cancer Research, 2023, 35, 343.
4 Yoon J W, Wang M Y. Journal of Neurosurgery:Spine, 2019, 30, 149.
5 Balytskyy V, Zakharash M, Kuryk O. Georgian Medical News, 2021, 318, 13.
6 Zhang S B, Chen Z R, Wu H Q, et al. Ultrasonics, 2023, 131, 106966.
7 Grube M, Weiss M, Walter C B, et al. Surgical Technology International, 2022, 40, 190.
8 Charoenkwan K, Iheozor-Ejiofor Z, Rerkasem K, et al. Cochrane Database of Systematic Reviews, 2017, 6, CD005987.
9 Lacitignola L, Desantis S, Izzo G, et al. Veterinary Sciences, 2020, 7, 8.
10 Ragab S M. The Journal of Laryngology & Otology, 2012, 126, 1056.
11 Lv M C. Study on the preparation and properties of medical anti-adhesion conductive surfaces. Master's Thesis, Dalian University of Technology, China, 2023 (in Chinese).
吕明川. 医用抗粘附导电表面的制备与性能研究. 硕士学位论文, 大连理工大学, 2023.
12 Dodde R E, Gee J S, Geiger J D, et al. IEEE Transactions on Bio-Medical Engineering, 2012, 59, 167.
13 You H, Yang Q. Chinese Journal of Medical Instrumentation, 2012, 36(4), 437 (in Chinese).
尤颢, 杨谦. 中国医疗器械杂志, 2012, 36(4), 437.
14 Charoenkwan K, Iheozor-Ejiofor Z, Rerkasem K, et al. Cochrane Database of Systematic Reviews, 2017, 6, 398.
15 Zhou C, Lu J, Wang X. Coatings, 2020, 10, 596.
16 Taibbi A, Furlan A, Sandonato L, et al. European Journal of Radiology, 2012, 81, 663.
17 Hill D S, O'Neill J K, Powel R J, et al. Reconstructive & Aesthetic Surgery, 2012, 65, 911.
18 Chino A, Karasawa T, Uragami N, et al. Gastrointestinal Endoscopy, 2004, 59, 374.
19 Liu H, Zhang L, Huang J, et al. Advances in Colloid and Interface Science, 2022, 300, 102584.
20 Zhu L B, Bao X. Surface and interface physics, Tianjin University Press, China, 1992, pp. 65 (in Chinese).
朱履冰, 包兴. 表面与界面物理, 天津大学出版社, 1992. pp. 65.
21 Xu B S, Zhu S H, Liu S C. Material surface engineering, Harbin Institute of Technology Press, China, 2014, pp. 134 (in Chinese).
徐滨士, 朱绍华, 刘世参. 材料表面工程, 哈尔滨工业大学出版社, 2014. pp. 134.
22 Liu C, Liao H D, Li Z E, et al. China Medical Device Information, 2024, 30(3), 60 (in Chinese).
刘草, 廖海东, 李蓁珥, 等. 中国医疗器械信息, 2024, 30(3), 60.
23 Yao G, Wu W S, Geng D X, et al. Chinese Journal of Mechanical Engineering, 2021, 57(1), 179 (in Chinese).
姚光, 武文帅, 耿大喜, 等. 机械工程学报, 2021, 57(1), 179.
24 Song T, Tian J, Xu F. China Medical Devices, 2016, 31(8), 75 (in Chinese).
宋涛, 田金, 许锋. 中国医疗设备, 2016, 31(8), 75.
25 Feldman L, Fuchshuber P, Jones D B. The SAGES manual on the fundamental use of surgical energy, Springer, New York, US, 2012, pp. 251.
26 Liu Z H, Wu F, Gu H, et al. Journal of Manufacturing Processes, 2023, 89, 444.
27 Zheng L, Wan J F, Long Y J, et al. Royal Society Open Science, 2018, 5, 125.
28 Wan J F. Study on electrode-sticking tissue interface bonding mechanism and anti-sticking electrode for electrosurgical instruments. Master's Thesis, Southwest Jiaotong University, China, 2018 (in Chinese).
万健飞. 高频电刀手术电极-粘附组织结合机制与抗粘附电极研究. 硕士学位论文. 西南交通大学, 2018.
29 Zhang W S. Metal World, 2020 (1), 21 (in Chinese).
张文毓. 金属世界, 2020 (1), 21.
30 Guo Q M, Qin Z H. Acta Physica Sinica, 2021, 70(2), 028101-1 (in Chinese).
郭秦敏, 秦志辉. 物理学报, 2021, 70(2), 028101-1.
31 Deng Y, Chen W L, Li B X, et al. Ceramics International, 2020, 46, 18373.
32 Sun X Y, Li Z M, Fu Q. ECS Journal of Solid State Science and Technology, 2021, 10, 8769.
33 Song C C, Yan X R, Zhang Z A, et al. Surface Technology, 2022, 51(12), 20 (in Chinese).
宋晨晨, 严新锐, 张子傲, 等. 表面技术, 2022, 51(12), 20.
34 Tomoyasu N, Masanori H, Ali A. Applied Surface Science, 2021, 552, 149373.
35 Li X, Xu Y Q, Chen Z Y. Surface Topography:Metrology and Properties, 2022, 10, 9.
36 Cheng H Y, Qu K L, Chiang H J, et al. Annals of Biomedical Engineering, 2015, 43, 2383.
37 Ching H A, Choudhury D, Nine M J, et al. Science and Technology of Advanced Materials, 2014, 15, 1.
38 Gao J, Cao Y, Ma Y, et al. Journal of Materials Engineering and Performance, 2022, 31, 8784.
39 Chen Y H, Chen W Y, Lin Y S. Journal of Materials Research and Technology, 2023, 25, 3803.
40 Castaño V M, Asamoah R B, Annan E A, et al. Advances in Materials Science and Engineering, 2020, 14, 145.
41 Alias R, Mahmoodian R, Abd Shukor M H. International Journal of Adhesion and Adhesives, 2019, 92, 89.
42 Hsu Y L, Lee C H, Chiu S M, et al. Defect and Diffusion Forum, 2010, 297-301, 656.
43 Ou K L, Chu J S, Surgical Endoscopy, 2014, 28, 2174.
44 Zhang D L, Wei E Z, Jing H, et al. Chinese Journal of Materials Research, 2021, 35(1), 7 (in Chinese).
张大磊, 魏恩泽, 荆赫, 等. 材料研究学报, 2021, 35(1), 7.
45 Jagielski J, Khanna A S, Kucinski J, et al. Applied Surface Science, 2020, 156, 47.
46 Nevelos J. The Knee, 2004, 11, 163.
47 Musil J, Zenkin S, Kos S, et al. Vacuum, 2016, 131, 34.
48 Yu W Y. Study on antiadhesion nitride coating for minimally invasive tungsten needle electrode by pvd technology. Master's Thesis, University of Shanghai for Science and Technology, China, 2021 (in Chinese).
郁王英. 基于PVD技术的微创钨针电极材料用氮化物抗粘连涂层的研究. 硕士学位论文, 上海理工大学, 2021.
49 Çeviker N, Keskil S, Baykaner K. Acta Neurochirurgica, 1998, 140, 619.
50 杨光, 段海真, 邓崇第, 等. 中国专利, CN201720045622, 2018.
51 Kaneko M, Hiratsuka M, Alanazi A, et al. Materials, 2021, 14, 376.
52 Shi X. Fabrication of functional nano polymer films via vapor-based route and its application in biomedicine. Master's Thesis, Ningbo University, China, 2019(in Chinese).
石枭. 气相法制备生物纳米涂层及其在生物医疗中的应用. 硕士学位论文, 宁波大学, 2019.
53 Park U N. ACS Biomaterials Science & Engineering, 2018, 4, 1891.
54 Zhou Y, Cheng X Y, Fang H, et al. Biomaterials Science, 2022, 10, 939.
55 Wang D W. Study on the synthesis of novel silicone anticoagulantive coating materials. Master's Thesis, Northwestern Polytechnical University, China, 2007(in Chinese).
王大伟. 新型有机硅抗凝血涂层材料的合成研究. 硕士学位论文, 西北工业大学, 2007.
56 Lu M C, Song L P, Li Y H, et al. Materials Letters, 2022, 313, 1.
57 Ren X X, Qiu Z G, Li Z Q. Coal Chemical Industry, 2021, 49(1), 18 (in Chinese).
任枭雄, 邱泽刚, 李志勤. 煤化工, 2021, 49(1), 18.
58 Jaurich H, Becerikli M, Zerrer J, et al. Journal of Reconstructive Microsurgery, 2022, 38, 47.
59 Wei C, Zhang G, Zhang Q, et al. ACS Applied Materials & Interfaces, 2016, 8, 34810.
60 简勇辉, 费凛. 中国专利, CN109938830B. 2021.
61 Zhang M L. Journal of Yunnan University(Natural Sciences Edition), 2005(S3), 462 (in Chinese).
张美玲. 云南大学学报(自然科学版), 2005(S3), 462.
62 Barthlott W, Neinhuis C. Planta, 1997, 202, 1.
63 Cheng C W, Lin C Y, Tseng W P, et al. US patent, US20130138103. 2013.
64 Han Z, Fu J, Fang Y, et al. Journal of Bionic Engineering, 2017, 14(3), 540.
65 韩志武, 曹会娜, 关会英, 等. 中国专利, CN103892905B, 2016.
66 Cao H N. Biomimetic anti-adhesive surface of minimally-invasive electrosurgical electrode. Master's Thesis, Jilin University, China, 2015 (in Chinese).
曹会娜. 微创手术器械高频电刀表面仿生脱附研究. 硕士学位论文, 吉林大学, 2015.
67 Wong T S, Kang S H, Tang S K, et al. Nature, 2011, 477, 443.
68 Liu G, Zhang P F, Liu Y. Micromachines. 2018, 9, 591.
69 Fu H L, Hao R F, Zheng J, et al. China Surface Engineering, 2016, 29(3), 304 (in Chinese).
付和林, 郝汝飞, 郑靖, 等. 中国表面工程, 2016, 29(3), 304.
70 Nie J L, Gu X L, Zhou L B. Journal of Biomedical Engineering Research, 2020, 39(1), 41 (in Chinese).
聂佳力, 谷雪莲, 周流斌. 生物医学工程研究, 2020, 39(1), 41.
71 Joseph R, Jues B, Scott M. Surgical Applications of Energy, 1998, 3249, 142.
72 Mikami T, Takahashi A, Hashi K, et al. Journal of Neurosurgery, 2004, 100, 133.
[1] 施宏玉, 邢冀琦, 薛培宏, 刘娟. 分子尺度下研究海洋污损生物的吸附机理[J]. 材料导报, 2023, 37(7): 21120126-7.
[2] 薛秀丽, 曾超峰, 王世斌, 李林安, 王志勇. 溶剂对PMMA基底上金属薄膜形貌的影响[J]. 材料导报, 2019, 33(z1): 412-415.
[3] 薛秀丽,王世斌,曾超峰,李林安,王志勇. 柔性基底上金属薄膜的失效行为及界面能测试方法研究进展[J]. 材料导报, 2020, 34(1): 1050-1058.
[1] JIN Qinglin, WANG Yang, CAO Lei, SONG Qunling. Effect of Nitriding in Mushy Zone on the Nitrogen Content and Solidification Transformation of Cr10Mn9Ni0.7 Alloy[J]. Materials Reports, 2018, 32(4): 579 -583 .
[2] WANG Shengmin, ZHAO Xiaojun, HE Mingyi. Research Status and Development of Mechanical Plating[J]. Materials Reports, 2017, 31(5): 117 -122 .
[3] HE Yuandong, SUN Changzhen, MAO Weiguo, MAO Yiqi, ZHANG Honglong, CHEN Yanfei, PEI Yongmao, FANG Daining. Measurement of Transverse Piezoelectric Coefficients of Pb(Zr0.52Ti0.48)O3 Thin Films by a Mechano-electrical Multiphysics Coupling, Bulge Test Method[J]. Materials Reports, 2017, 31(15): 139 -144 .
[4] TAO Lei, ZHENG Yunwu,DI Mingwei, ZHANG Yanhua, ZHENG Zhifeng. Preparation of Porous Carbon Nanofiber from Liquid Phenolic Resin and Its Characterization[J]. Materials Reports, 2017, 31(10): 101 -106 .
[5] SU Lan, ZHANG Chubo, WANG Zhen, MI Zhenli. Finite Element Simulation of Electromagnetic Induction Heating in Hot Metal Gas Forming[J]. Materials Reports, 2017, 31(24): 182 -177 .
[6] QI Yaping, LUO Faliang, WANG Kezhi, SHEN Zhiyuan, WU Xuejian, WANG Diran. Effect of TMC-300 on the Performance of PLLA/PPC Alloy[J]. Materials Reports, 2018, 32(10): 1672 -1677 .
[7] LIU Huan, HUA Zhongsheng, HE Jiwen, TANG Zetao, ZHANG Weiwei, LYU Huihong. Indium Recovery from Waste Indium Tin Oxide: a Technological Review[J]. Materials Reports, 2018, 32(11): 1916 -1923 .
[8] DU Min, SONG Dian, XIE Ling, ZHOU Yuxiang, LI Desheng, ZHU Jixin. Electrospinning in Rechargeable Ion Batteries for High Efficient Energy Storage[J]. Materials Reports, 2018, 32(19): 3281 -3294 .
[9] LIU Xiao, XU Qian, LAI Guanghong, GUAN Jianan, XIA Chunlei, WANG Ziming, CUI Suping. Application Performances and Mechanism of Polycarboxylic Acid in Different Comb-bonded Structures in High-performance Concrete[J]. Materials Reports, 2018, 32(22): 4011 -4015 .
[10] ZHANG Di, YANG Di, XU Cui, ZHOU Riyu, LI Hao, LI Jing, WANG Peng. Study on Mechanism of Highly Effective Adsorption of Bisphenol F by Reduced Graphene Oxide[J]. Materials Reports, 2019, 33(6): 954 -959 .
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed