INORGANIC MATERIALS AND CERAMIC MATRIX COMPOSITES |
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Applications of Graphene Nanocomposites in Electrochemical Nucleic Acid Sensors |
LI Yating, LIU Zhongming, CHEN Yu, GUO Yantong, YANG Huan, ZHANG Haiyan*
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General Hospital of Southern Theatre Command, Guangzhou 510010, China |
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Abstract In recent years, the demand for nucleic acid detection is gradually increased in various fields, and the development of nucleic acid molecular detection devices with high sensitivity and specificity has become a hot research nowadays. Among these studies, electrochemical detection devices have the advantages of fast response, simple operation, portability, and low production cost. For the development of electrochemical sensors, one of the most important parts is the selection of electrode materials. Graphene and its derivatives not only have excellent electrical, mechanical, and electrochemical properties, but are also capable of forming nanocomposites with metal nanoparticles, metal oxides, metal organic frameworks, polymers, and ionic liquids. Electrochemical sensors based on these nanocomposites have already played an important role in the detection of nucleic acids. Here, the unique structural properties of graphene and its derivatives are first introduced, followed by a classification of graphene electrochemical sensing based on different graphene nanocomposites, and finally the application scenarios of electrochemical sensors for nucleic acid detection are explored, and the prospects for the development of graphene electrochemical sensors are discussed and looked into.
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Published: 25 December 2024
Online: 2024-12-20
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