| POLYMERS AND POLYMER MATRIX COMPOSITES |
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| Research Progress of Metal-Organic Hybrid Materials for Detection and Decontamination of Organophosphate Agents |
| LIANG Feipan1,†, WU Si1,†, XIA Yuzheng1, SHI Shuxian1,*, NIE Zhiyong2,*
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1 College of Materials Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China
2 Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China |
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Abstract Nerve agents and most organophosphate pesticides belong to organophosphate agent, which can inhibit acetylcholinesterase activity in the human body, leading to the accumulation of excessive acetylcholine in the body, causing a series of health problems and even death. Although the detection of organophosphorus agent by traditional large-scale instruments has high accuracy, the detection should spend more time, sample processing is complicated, and professional instruments and technical personnel are required. How to quickly detect, identify and decontaminate organophosphorus agent in a timely manner has important practical significance for the early prevention and treatment of poisoning, even saving lives. This paper summarizes the detection and decontamination of organophosphorus agents by two metal-organic hybrid materials based on the compounds of precious metal nanoparticles and organic chemicals, metal-organic framework materials. The progress of fluorescence and colorimetric methods used to detect organophosphorus agents directly by color or fluorescence change quickly in a short time. The effect of adsorption and degradation of organophosphorus poisons caused by metal-organic framework materials, and the prospect of future development in this field are introduced.
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Published: 10 July 2022
Online: 2022-07-12
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| Fund:Military Research Projects. |
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