纳米材料掺杂型聚乙烯醇双交联复合水凝胶的力-化学性质

doi:10.11896/cldb.18010247

Abstract
Figure/Table
References
Related Citation (15)

Download:

Full Text ( PDF ) (12913KB)
Export: BibTeX | EndNote (RIS)

Abstract In the present work, a series of graphene oxide (GO)/hydroxyapatite (HA)/poly(vinyl alcohol)(PVA) dual cross-linked composite hydrogels were synthesized by applying the combinatorial methods of chemical crosslinking and cyclic freezing-thawing, and varying the mass ra-tios of GO to PVA, HA to PVA and the number of times of cyclic freezing-thawing. Firstly, PVA chains covalently crosslinked at a rather low concentration (considering the bio-safety) of glutaraldehyde for the chemical-crosslinking of the first network. Then, during the cyclic freezing-thawing process, the PVA crystalline domains served as cross-linking knots and the hydrogen-bonding were formed for the secondary physical-crosslinking network. The resultant hydrogels were defined as the GO/HA/PVA dual cross-linked hydrogels. The structure of the GO/HA/PVA nanocomposite hydrogels was characterized by the high-resolution scanning electron microscope and X-ray diffraction. The tensile mechanical properties were further investigated for the dual cross-linked hydrogels differing in mass ratios of GO to PVA (0%—2.6%) and HA to PVA (0.22—1.10), and number of times of cyclic freezing-thawing (0, 3, 7). When the mass ratio of GO/PVA reached to 1.9%, HA/PVA reached to 0.66 and with 7 times cyclic freezing-thawing, the GO/HA/PVA dual cross-linked hydrogel achieved the maximum tensile strength and elongation at break of up to 695 kPa and 286%, and the Young's modulus was 78 kPa. We further investigated the water content and swelling behaviors of dual cross-linked hydrogels with various number of times of cyclic freezing-thawing (0, 3, 7). The results revealed that the water content was about 79.3%—81.7%, and the equilibrium swelling ratio was about 50.1%—72%. The hydrogel was expected to serve as cartilage substitution materials in clinical medicine field.

Key words： poly(vinyl alcohol) graphene oxide composite hydrogel dual cross-linking tensile strength

Published: 16 May 2019

CLC number:

R318.08

Fund:This work was financially supported by the National Natural Science Foundation of China (11702183, 11632013, 11572213,11872262), Natural Science Foundation of Shanxi (2016021145), the State Key Laboratory of Fine Chemicals (KF1511), the State Key Laboratory of Luminescent Materials and Devices (2019-skllmd-21).

About author:: Yanan Xue currently works at Taiyuan University of Technology. At present, the main research direction is the fabrication of biomedical polymer materials and the analysis of mechanical and chemical properties.
Yanqin Wang received her Ph.D. degree in analytical chemistry from the Nankai university in 2013 and served in Taiyuan university of technology till now. She is currently an associate professor and master supervisor enjoying the National Natural Science Youth Fund, Natural Science Foundation of Shanxi Youth Fund. Her team's research interests focus on the fabrication of the biome-dical polymer materials and nano fluorescence sensors.

	Service
	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	XUE Yanan
	HAN Zhengxue
	LI Shuangran
	ZHANG Jiayu
	ZHANG Xuehui
	WANG Zhaowei
	JIA Ruijie
	WANG Yanqin
	WU Xiaogang
	LI Xiaona
	CHEN Weiyi

Cite this article:

XUE Yanan,HAN Zhengxue,LI Shuangran, et al. Mechanical-Chemical Properties of Nanomaterial Doped Poly(vinyl alcohol) Dual Cross-linked Hydrogels[J]. Materials Reports, 2019, 33(10): 1745-1751.

URL:

http://www.mater-rep.com/EN/10.11896/cldb.18010247 OR http://www.mater-rep.com/EN/Y2019/V33/I10/1745

1 Li W, Feng X, Chen R S. Polymer, 2005,46(25), 12026.
2 Jiang B. Journal of Applied Polymer Science, 2010,46(5), 783.
3 Spoljaric S, Salminen A, Luong N D, et al. European Polymer Journal, 2014,56(7), 105.
4 Sun T Y, Liang L J, Wang Q, et al. Biomaterials Science, 2014,2(3), 419.
5 Yang W T, Zhang L H, Ma Y H, et al. Journal of Materials Chemistry B, 2015,3(39), 7673.
6 Du Z S, Hu Y, Gu X Y, et al. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2016,489, 1.
7 Chen S, Zhang M, Shao X, et al. Journal of Materials Chemistry B, 2015,3(33), 6798.
8 Nakajima T, Takedomi N, Gong J P, et al. Polymer Chemistry, 2010,1(5), 693.
9 Kim T H, Dan B A, Oh S H, et al. Biomaterials, 2015,40, 51.
10 Gong J P. Soft Matter, 2010,6(12), 2583.
11 Gong J P, Katsuyama Y, Kurokawa T, et al. Advanced Materials, 2003,15(14), 1155.
12 Kamata H, Akagi Y, Kayasugakariya Y, et al. Science, 2014,343(6173), 873.
13 Hu J, Hiwatashi K, Gong J P, et al. Macromolecules, 2011,44(19), 7775.
14 Tuncaboylu D C, Sari M, Oppermann W, et al. Macromolecules, 2011,44(12), 4997.
15 Nakajima T, Furukawa H, Gong J P, et al. Macromolecules, 2009,42(6), 2184.
16 Tian S, Shan G R, Wang L Y. Acta Polymerica Sinica, 2010(10), 1175(in Chinese).
田帅, 单国荣, 王露一. 高分子学报, 2010(10), 1175.
17 Myung D, Koh W, Frank C W, et al. Polymer, 2007,48(18), 5376.
18 Belay M, Sonker A K, Nagarale R K, et al. Polymer International, 2017,66, 1737.
19 Tang Y, Pang L B, Wang D P. Journal of Non-Crystalline Solids, 2017,476, 25.
20 Xue F. Preparation and study on properties of PVA composite hydrogel. Master's Thesis, Southwest Petroleum University, China, 2016 (in Chinese).
薛飞. PVA复合水凝胶的制备及其性能研究. 硕士学位论文,西南石油大学, 2016.
21 Wang F. The synthesis and physicochemical properties of poly(vinyl alcohol)-gellan gun composite hydrogel. Master's Thesis,Soochow University, China,2016 (in Chinese).
王飞. 聚乙烯醇-结冷胶复合水凝胶的制备和物理化学性质研究.硕士学位论文,苏州大学, 2016.
22 Wang T, Hu X B, Liu X X, et al. Scientia Sinica Chimica, 2012,42(5), 650(in Chinese).
王涛, 胡小波, 刘新星,等. 中国科学:化学, 2012,42(5), 650.
23 Chetty A, Steynberg T, Moolman S, et al. Journal of Biomedical Mate-rials Research Part A, 2008,84(2), 475.
24 Liang J J, Huang Y, Zhang L, et al. Advanced Functional Materials, 2010,19(14), 2297.
25 Han X F, Qi D D, Zhang L, et al. Acta Polymerica Sinica, 2014(2), 218(in Chinese).
韩哓芳, 齐栋栋, 张玲,等. 高分子学报, 2014(2), 218.
26 Zhang L, Wang Z, Gao J, et al. Journal of Materials Chemistry, 2011,21(28), 10399.
27 Shen Y Q, Chen K, Dai Z M. Materials Review B:Research Papers, 2015,29(5), 73(in Chinese).
沈艳秋, 陈凯, 戴祖明. 材料导报:研究篇, 2015,29(5), 73.
28 Marcano D C, Kosynkin D V, Berlin J M, et al. ACS Nano, 2010,4(8), 4806.
29 Zhang H, Zhai D, He Y. RSC Advances, 2014,4(84), 44600.
30 Kong W, Huang D, Xu G, et al. Chemistry-An Asian Journal, 2016,11(11), 1697.
31 Hu M, Gu X, Hu Y, et al. Macromolecular Materials and Engineering, 2016,301(11), 1352.
32 Zhang L, Li Y B, Wei J, et al. Journal of Functional Materials, 2005,36(3), 441(in Chinese).
张利,李玉宝,魏杰,等. 功能材料, 2005,36(3), 441.
33 Pan Y S. Study on preparation of n-HA/PVA gels as articular cartilage repair material. Ph.D. Thesis, Nanjing University of Science and Technology, China, 2007 (in Chinese).
潘育松. n-HA/PVA凝胶关节软骨修复材料制备与性能研究. 博士学位论文,南京理工大学, 2007.
34 Lin P, Ma S H, Wang X L, et al. Advanced Materials, 2015,27(12), 2054.