静电纺纳米纤维基水凝胶伤口敷料的制备策略及应用研究进展

doi:10.11896/cldb.25010089

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Abstract Hydrogels are a promising type of wound dressing due to their excellent hydrophilicity, high swelling rate, and three-dimensional porous structure. However, using pure hydrogels can lead to the limited functionality and application in wound dressings because of the difficulty of simulating the complex three-dimensional micro-nanofiber structure of the extracellular matrix. In recent years, electrospun nanofiber-based hydrogel wound dressings have combined the advantages of electrospun nanofibers and hydrogels, offering customizable three-dimensional spatial structures, large specific surface area, high porosity, enhanced mechanical properties, and improved biofunctionality, expanding their applications. This review summarizes the preparation strategies of electrospun nanofiber-based hydrogel wound dressings, including sol-gelatinization, electrostatic spraying, lamination, dispersion, 3D printing, and direct electrostatic spinning method. It then discusses their characteristics and applications, and finally summarizes and outlines the future research directions in this field.

Key words： electrospun nanofiber-based hydrogel wound dressings preparation strategy

Published: 10 January 2026 Online: 2026-01-09

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TS106

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	HOU Kexin

Cite this article:

HOU Kexin. Research Progress on the Preparation Strategies and Applications of Electrospun Nanofiber-based Hydrogel Wound Dressings[J]. Materials Reports, 2026, 40(1): 25010089-9.

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https://www.mater-rep.com/EN/10.11896/cldb.25010089 OR https://www.mater-rep.com/EN/Y2026/V40/I1/25010089

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