RESEARCH PAPER |
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Surface Modification of Collagen Films with Dopamine to Promote Cell Adhesion and Proliferation |
CUI Guolian, DAN Nianhua, DAN Weihua
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Key Laboratory of Leather Chemistry and EngineeringSichuan University,Ministry of Education;The Research Center of Biomedical Engineering and Technology, Sichuan University, Chengdu 610065; |
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Abstract Dopamine has been widely used to surface modify materials due to its multi-functional reactivity and biocompatibility. Herein, in order to investigate whether the mechanical strength, hydrothermal stability, hydrophilic property and biocompatibility of collagen films are influenced, dopamine was used to surface-modify collagen films, and then the films were characterized. Results showed that the triple helix structure of collagen remains intact, and mechanical strength, hydrothermal stability and hydrophi-lic property of the films are enhanced. Besides, the films can promote adhesion and proliferation of fibroblasts.
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Published: 25 January 2017
Online: 2018-05-02
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