金纳米材料光学传感快速检测方法研究要点初探

doi:10.11896/cldb.20050221

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Abstract Based on the excellent optical properties, good stability and easy surface functionalization of gold nano-materials, the nano-gold optical sen-sing detection method is established, which has the advantages of high sensitivity, rapid detection, easy operation, visualization, and low cost. This type of sensor makes use of the interaction between functionalized gold nanoparticles and the target to show different colors, fluorescence quenching and scattering intensity changes due to the change of size, shape and aggregation state of gold nanoparticles, which provides an excellent detection platform for the rapid detection of the target.
In this review, four common nano-gold optical sensing detection methods have been summarized to better introduce the important role of gold nanomaterials in the modern detection field, including nano-gold aggregation optical sensing method, nano-gold etching optical sensing method, nano-gold fluorescence optical sensing method, and nano-gold scattering optical sensing method. Through introducing the detection principles of these different strategies, the development and applications of nano-gold optical sensors in chemical, biological and environmental fields are discussed. Subsequently, through analyzing these four methods' experimental design ideas, seven points for the development of nano-gold optical sensing method are preliminarily summarized, namely: gold nanoparticles synthesis and surface functionalization, solution pH, reaction temperature and reaction time, selectivity, system detection limit, method accuracy, and system reusability. Through analyzing the importance of these experimental points, it will provide scientific researchers with reference of experimental design ideas and experience.
Finally, this review discusses several challenges of current nano-gold optical sensing detection methods and forecasts its' future development direction. For example, the technologies of smart phones and immunochromatographic strips can be combined with such methods to realize the simplification and portability in the process of detection. In general, it will have a good development prospect for the optical sensing detection method based on gold nanomaterials.

Key words： gold nanoparticles synthesis method functionalization optical sensor rapid detection

Published: 03 November 2021

CLC number:

TB383

Fund:Key Fields of Ordinary Universities in Guangdong Province (Rural Revitalization) (2020ZDZX1009), Fundamental Research Project of Shenzhen Science and Technology Program (JCYJ20190813103601660), Self-made Experimental Instrument Equipment Fund of Shenzhen Technology University (2020XZY009).

About author:: Shengliang Zhao received his bachelor's degree in engineering from North University of China in June 2018. He is currently a graduate student of the College of Applied Technology of Shenzhen University and is conducting research under the guidance of professor Liqiong Chen. At present, the main research field is the research of nano-gold visual rapid detection method.
Liqiong Chen is a professor and master tutor of the School of New Materials and New Energy of Shenzhen University of Technology. In June 2000, she graduated from the School of Chemistry and Chemical Enginee-ring, Sun Yat-Sen University. In June 2009, she obtained a Ph.D. from the School of Chemistry and Chemical Engineering, Sun Yat-Sen University. From 2003 to 2010, worked in the Institute of New Materials and Biomedicine, Shenzhen Tsinghua University Research Institute, as an engineer/deputy director of the laboratory; From 2010 to 2017, worked as the laboratory director of the Chemical Product Testing Institute of the Shenzhen Institute of Metrology and Quality Inspection; 2018 to present, she workes as a professor at the School of New Materials and New Energy, Shenzhen Technology University. She mainly engages in the research of controllable preparation and analysis and testing of nanomaterials, rapid detection technology and equipment, instrument analysis and testing and standards. In recent years, she has been engaged in the preparation and application of nanomaterials, material quality testing and standardization research, and published more than 10 academic papers.

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Cite this article:

ZHAO Shengliang,LIU Feiyan,CHEN Liqiong. Review on the Key Points of the Rapid Detection Methods Based on Gold Nanomaterial Optical Sensors[J]. Materials Reports, 2021, 35(19): 19099-19115.

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http://www.mater-rep.com/EN/10.11896/cldb.20050221 OR http://www.mater-rep.com/EN/Y2021/V35/I19/19099

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