修饰纳米CeO<sub>2</sub>的制备及其复合纤维膜对体外磷活性影响研究

doi:10.11896/cldb.25040225

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Abstract Cerium oxide nanoparticles (CeO₂ NPs) were synthesized via a chemical precipitation method and subsequently surface-modified with sodium citrate (MCeO₂) to enhance their dispersibility and enzyme-mimetic catalytic properties. Morphological characterization was performed using transmission electron microscopy (TEM), while X-ray photoelectron spectroscopy (XPS) and Raman spectroscopy were employed for semi-quantitative analysis of Ce³⁺ content and relative oxygen vacancy concentration. The findings show that although the citrate modification reduces both Ce³⁺ content and oxygen vacancy concentration, it significantly improves the catalytic dephosphorylation activity and dispersibility of MCeO₂. Further fabrication of polyurethane-supported MCeO₂ fiber membranes via electrospinning demonstrates that the modified MCeO₂ maintains excellent dispersibility within the polymer matrix even at high loading concentrations, while exhibiting markedly superior catalytic dephosphorylation efficiency compared to unmodified sample. CCK-8 assays confirm good cytocompatibility, and alkaline phosphatase staining further reveals the osteogenic induction potential of these fiber membranes. This study provides valuable insights for developing nanocomposite biomaterials with optimal dispersibility and efficient catalytic dephosphorylation activity.

Key words： cerium oxide nanoparticles sodium citrate modification electrospun polyurethane-based fiber dispersibility catalytic dephosphorization activity

Published: 10 November 2025 Online: 2025-11-10

CLC number:

TB32

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	Articles by authors
	LI Yuping
	ZHAO Qing
	ZHANG Jinzheng
	LEI Xiaoyu
	LI Li
	MU Bo
	DU Qingda
	LI Yubao
	WANG Jian
	ZUO Yi

Cite this article:

LI Yuping,ZHAO Qing,ZHANG Jinzheng, et al. Fabrication of Modified Nano-CeO₂ and Their Composite Fibrous Membranes for Enhanced Phosphorus Activity: an in vitro Study[J]. Materials Reports, 2025, 39(21): 25040225-7.

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https://www.mater-rep.com/EN/10.11896/cldb.25040225 OR https://www.mater-rep.com/EN/Y2025/V39/I21/25040225

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