胶原基复合止血材料的研究进展及展望

doi:10.11896/cldb.21030008

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Abstract Collagen can be used in various hemostatic scenarios and has gradually replaced traditional hemostatic materials due to its superior perfor-mance and easy procurement from animals. However, regardless of form, collagen hemostatic agents have disadvantages such as poor mechanical properties and weak adhesion. Although purifying or modifying the cross-linking agent of such hemostatic agents can improve their performance to some extent, their fundamental structure has not been effectively changed, limiting clinical application. Natural biomaterials or their derivatives are rich sources of biocompatible hemostatic agents with sound absorption and degradation properties. Collagen-based composite hemostatic materials formed by cross-linking collagen with natural biomaterials or derivatives show significantly improved performances and have become valuable biomedical materials. The widely used materials for this purpose include chitosan, fibrin glue, alginate, and oxidized cellulose. Additionally, the application of traditional Chinese medicinal materials has gradually gained attention in recent years. This article reviews the research progress on different types of collagen-based hemostatic materials and summarizes their respective advantages and disadvantages. Finally, the future direction of developing of collagen-based composite hemostatic materials is discussed.

Key words： collagen hemostasis chitosan oxidized cellulose fibrin glue alginate traditional Chinese medicinal materials

Published: 10 March 2023 Online: 2023-03-14

CLC number:

O636.9

Fund:Opening Project of Key Laboratory of Leather Chemistry and Engineering (SCU2021D005), the Fundamental Research Funds for the Central Universities (20826041E4156), and the National Natural Science Foundation of China (514730001).

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	YAN Xingyu
	DAN Nianhua
	CHEN Yining
	DAN Weihua
	LI Zhengjun

Cite this article:

YAN Xingyu,DAN Nianhua,CHEN Yining, et al. Research Progress and Development Direction of Collagen-based Composite Hemostatic Materials[J]. Materials Reports, 2023, 37(5): 21030008-9.

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http://www.mater-rep.com/EN/10.11896/cldb.21030008 OR http://www.mater-rep.com/EN/Y2023/V37/I5/21030008

1 Kauvar D S, Lefering R, Wade C E. Journal of Trauma & Acute Care Surgery, 2006, 60(6), S3.
2 Hamada S R, Rosa A, Gauss T, et al. Critical Care, 2018, 22(1), 113.
3 Chen G B, Yang H, Zhou J Y, et al. Journal of Chongqing University of Technology(Natural Science), 2022, 36(2), 214.
陈国宝, 杨欢, 周江一, 等. 重庆理工大学学报(自然科学), 2022, 36(2), 214.
4 Wang Q, Li L, Wang H R, et al. Journal of Functional Materials, 2021, 52(1), 1214.
王倩, 李莉, 王焕然, 等. 功能材料, 2021, 52(1), 1214.
5 Luo Y R, Lu C L, Yang D X, et al. Journal of Functional Materials, 2022, 53(8), 8054.
罗艳荣, 卢春兰, 杨东旭, 等. 功能材料, 2022, 53(8), 8054.
6 Zou Y, Liu W J. The Science and Technology of Gelatin, 2010, 30(1), 6 (in Chinese).
邹勇, 刘文杰. 明胶科学与技术, 2010, 30(1), 6.
7 Zhang Z, Cong Y L, Tu Z G. Chinese Journal of Laboratory Medicine, 2006, 29(5), 428 (in Chinese).
张卓, 丛玉隆, 涂植光. 中华检验医学杂志, 2006, 29(5), 428.
8 Sun L, Li B, Jiang D, et al. Colloids & Surfaces B Biointerfaces, 2017, 159, 89.
9 Cheng X, Shao Z, Li C, et al. Plos One, 2017, 12(1), e0169731.
10 Jiang X, Wang Y, Fan D, et al. Journal of Biomaterials Applications, 2017, 31(8), 1099.
11 Duan Z G. The study on the properties of human-like collagen hematisc-hesis sponge, Master's Thesis, Northwest University, China, 2008 (in Chinese).
段志广. 类人胶原蛋白止血海绵的性能研究. 硕士学位论文, 西北大学, 2008.
12 Muthukumar T, Prabu P, Ghosh K, et al. Colloids & Surfaces B Bioin-terfaces, 2014, 113, 207.
13 Wang X. Journal of Bioactive and Compatible Polymers, 2006, 21(1), 39.
14 Lyu X Y, Ou M M, Huang X F. Journal of Clinical and Experimental Medicine, 2019, 18(17), 1796 (in Chinese).
吕晓玉, 欧明明, 黄晓峰. 临床和实验医学杂志, 2019, 18(17), 1796.
15 Kikuchi M, Matsumoto H N, Yamada T, et al. Biomaterials, 2004, 25(1), 63.
16 Cheung D T, Nimni M E. Connective Tissue Research, 1982, 10(2), 187.
17 Sung H W, Hsu H L, Shih C C, et al. Biomaterials, 1996, 17(14), 1405.
18 Drexler J W, Powell H M. Tissue Engineering: Part C, 2011, 17(1), 9.
19 Hu Y, Liu L, Dan W, et al. International Journal of Biological Macromolecules, 2013, 55, 221.
20 Bai Z X, Dan N H, Dan W H, et al. Materials Reports B:Resperch Papers, 2018, 32(10), 3628 (in Chinese).
白忠祥, 但年华, 但卫华, 等. 材料导报:研究篇, 2018, 32(10), 3628.
21 Pei Y, Zheng X J, Tang K Y. Chinese Polymer Bulletin, 2010(2), 58 (in Chinese).
裴莹, 郑学晶, 汤克勇. 高分子通报, 2010(2), 58.
22 Liu X H. West Leather, 2012, 34(8), 13 (in Chinese).
刘新华. 西部皮革, 2012, 34(8), 13.
23 Rao S B, Sharma C P. Journal of Biomedical Materials Research, 1997, 34(1), 21.
24 Benesch J, Tengvall P. Biomaterials, 2002, 23(12), 2561.
25 Hu Z, Zhang D Y, Lu S T, et al. Marine Drugs, 2018, 16(8),273.
26 Yan T S, Cheng F, Wei X J, et al. Carbohydrate Polymers, 2017, 170, 271.
27 Zheng C, Liu X, Luo X, et al. Journal of Materials Chemistry B, 2019, 7(46), 7338.
28 Ma M. Study of biocompatibility and hemostatic effect of chitosan-human-like collagen sponge, Master's Thesis, Northwest University, China, 2008 (in Chinese).
马茂. 壳聚糖-类人胶原蛋白海绵的生物相容性及止血效果研究. 硕士学位论文, 西北大学, 2008.
29 Wang Y, Huang Y, Lin C P, et al. Fujian Journal of Agricultural Sciences, 2013, 28(4), 315 (in Chinese).
王茵, 黄煜, 林彩平, 等. 福建农业学报, 2013, 28(4), 315.
30 Chen M M, Huang Y Q, Hao G, et al. Journal of Applied Polymer Science, 2015, 131(21), 8558.
31 Shi X, Fang Q, Ding M, et al. Journal of Biomaterials Applications, 2016, 30(7), 1092.
32 Ding C C, Tian M D, Feng R, et al. ACS Biomaterials Science & Engineering, 2020, 6(7), 3855.
33 Zhao S H, Hu Q L, Zhong Z Y, et al. Chinese Journal of Comparative Medicine, 2010(5), 61 (in Chinese).
赵士海, 胡庆柳, 钟志勇, 等. 中国比较医学杂志, 2010(5), 61.
34 Zhao H Q, Wang D T. Chinese Journal of Veterinary Medicine, 2003, 2003(1), 17 (in Chinese).
赵海全, 王冬桃. 中国兽医杂志, 2003, 2003(1), 17.
35 Zhang S D. Guide of China Medicine, 2013, 11(16), 98 (in Chinese).
张松达. 中国医药指南, 2013, 11(16), 98.
36 Meng Z Y, Dou G F, Liu M X, et al. Military Medical Sciences, 2002, 26(1), 51 (in Chinese).
孟志云, 窦桂芳, 刘敏霞, 等. 军事医学科学院院刊, 2002, 26(1), 51.
37 Spotnitz W D. ISRN Surgery, 2014, 2014, 203943.
38 Stalker T J, Welsh J D, Tomaiuolo M, et al. Blood, 2014, 124(11), 1824.
39 Janmey P A, Winer J P, Weisel J W. Journal of the Royal Society Interface, 2009, 6(30), 1.
40 Li W D, Deng L J, Fan H H, et al. In: Conference Proceedings of the 22nd Guangdong Pharmacist Week Conference in 2016. Guangdong, 2016, pp.1292 (in Chinese).
李伟达, 邓乐君, 樊鸿浩, 等. 2016年广东省药师周大会论文集, 2016, pp.1292.
41 Wang Y, Lu W. Journal of Biomedical Engineering, 2009, 2009(4), 922 (in Chinese).
王勇, 陆伟. 生物医学工程学杂志, 2009, 2009(4), 922.
42 Dickneite G, Metzner H J, Kroez M, et al. Journal of Surgical Research, 2002, 107(2), 186.
43 Zhang D X, He Z X. Chinese Journal of Critical Care Medicine, 2005, 25(5), 353 (in Chinese).
张德兴, 何忠杰. 中国急救医学, 2005, 25(5), 353.
44 Pallaske F, Seebauer C, Kaltofen D, et al. Journal of Visceral Surgery, 2021, 158(1), 11.
45 Zhao X, Cao X H, Ma Y Y, et al. Chinese Journal of Blood Transfusion, 2010, 23(4), 250 (in Chinese).
赵雄, 曹晓涵, 马玉媛, 等. 中国输血杂志, 2010, 23(4), 250.
46 Wang Q Z, Wang C H, Zhang W B, et al. China Medical Herald, 2010, 2010(17), 53 (in Chinese).
王秋卓, 王彩虹, 张文博, 等. 中国医药导报, 2010, 2010(17), 53.
47 Li W D, Deng L J, Li J, et al. Shandong Medical Journal, 2017, 2017(9), 31 (in Chinese).
李伟达, 邓乐君, 李健, 等. 山东医药, 2017, 2017(9), 31.
48 Croisier F, Jérme C. European Polymer Journal, 2013, 49(4), 780.
49 Segal H C, Hunt B J, Gilding K. Journal of Biomaterials Applications, 1998, 12(3), 249.
50 Huang H, Chen H, Wang X, et al. ACS Biomaterials Ence & Engineering, 2019, 5(10), 549
51 Bo R L, Jin W H, Choi Y Y, et al. Biomaterials, 2012, 33(3), 837.
52 Jun Y, Kang A R, Lee J S, et al. Biomaterials, 2013, 34(15), 3784.
53 Wu J, Wang G H, Zhang H, et al. Key Engineering Materials, 2011, 474-476, 1935.
54 Jin J, Ji Z, Xu M, et al. ACS Biomaterials Science & Engineering, 2018, 4(7), 2541.
55 Liu C, Shi Z, Sun H, et al. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 2020, 109(8), 1116.
56 Zong J. The study on the anti-immersed collagen combined medical dressing, Master's Thesis, Shanghai Ocean University, China, 2016 (in Chinese).
宗杰. 防海水浸泡胶原蛋白复合医用敷料研究. 硕士学位论文, 上海海洋大学, 2016.
57 Song Y Z, Ren Y, Lou R Y, et al. Journal of Functional Materials, 2016, 47(11), 136 (in Chinese).
宋益哲, 任英, 娄茹云, 等. 功能材料, 2016, 47(11), 136.
58 Guo W Y, Guo L L, Liu Z Y, et al. New Chemical Materials, 2019, 47(11), 162 (in Chinese).
刘文迎, 郭亮亮, 刘泽员, 等. 化工新型材料, 2019, 47(11), 162.
59 Zhang X, Zhou H, Yang Y H, et al. Chemical Journal of Chinese Universities, 2015, 36(10), 2040 (in Chinese).
张霞, 周浩, 杨宇红, 等. 高等学校化学学报, 2015, 36(10), 2040.
60 Palm M D, Altman J S, et al. Dermatol Surg, 2008, 34(4), 431.
61 Nicola T, Di L A, Vincenzo L, et al. Surgery Research and Practice, 2016, 2016, 3058754.
62 Slezak P, Monforte X, Ferguson J, et al. Journal of Materials Science Materials in Medicine, 2018, 29(6), 71.
63 Kakaei F, Seyyed Sadeghi M S, Sanei B, et al. HPB Surgery, 2013, 2013, 587608.
64 Cheng W, Li H, Zheng X, et al. Physical Chemistry Chemical Physics Pccp, 2016, 18(42), 29183.
65 Ponni R, Vuorinen T, Kontturi E. Bioresources, 2012, 7(4), 6077.
66 Kamel S, Ali N, Jahangir K, et al. Express Polymer Letters, 2008, 2(11), 758.
67 Baker A A, Helbert W, Sugiyama J, et al. Applied Physics A-Materials Science & Processing, 1998, 66, S559.
68 Knight P E, Podczeck F, Newton J M. Journal of Pharmaceutical Sciences, 2009, 98(6), 2160.
69 Eichhorn S J, Young R J. Cellulose, 2001, 8(3), 197.
70 Wu Q, Henriksson M, Liu X, et al. Biomacromolecules, 2007, 8(12), 3687.
71 Cheng W, He J, Chen M, et al. Fibers and Polymers, 2016, 17(8), 1277.
72 Li H, Cheng W, Liu K, et al. Carbohydrate Polymers, 2017, 165, 30.
73 Han Z B, Xie J X. Guangxi Journal of Traditional Chinese Medicine, 2009, 32(2), 6 (in Chinese).
韩邦志, 谢金鲜. 广西中医药, 2009, 32(2), 6.
74 Gallardo R, Aguilar M, Silva P, et al. Carbohydrate Polymers, 2018, 192, 84.
75 Luisa G C, Claudia C, Martha L. Marine Drugs, 2017, 15(10), 328.
76 Li F, Luo P, Liu H. Marine Drugs, 2018, 16(4), 106.
77 Lu B, Hu S S, Zhu X, et al. Health Research, 2011, 31(2), 94 (in Chinese).
卢斌, 胡思思, 诸娴, 等. 健康研究, 2011, 31(2), 94.
78 Ma C X. The study of the Yunnan Baiyao and Panax Notoginseng Saponins spring on the anastomosis. Master's Thesis, University of South China, China, 2012 (in Chinese).
马传勋. 云南白药及其活性成分三七总皂苷对肠吻合口的作用研究. 硕士学位论文, 南华大学, 2012.
79 Liu X H. Preparation and evaluation of two novel functional hemostatic biomaterials based on the most advanced collagen aggregate. Ph. D. Thesis, Sichuan University, China, 2017 (in Chinese).
刘新华. 基于高层级胶原聚集体的功能性止血材料的制备与性能. 博士学位论文, 四川大学, 2017.
80 Liu W. Collagen extracted from fetal bovine and application on hemostatic material, Master's Thesis, Sichuan University, China, 2018 (in Chinese).
刘伟. 胎牛皮源胶原的提取及在止血材料中的应用. 硕士学位论文, 四川大学, 2018.