基于壳聚糖的分子印迹技术研究及应用

doi:10.11896/cldb.21040121

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Abstract Molecular imprinting technology is a new molecular recognition technology by which the polymers with specific and selective recognition ability could be prepared. With high specificity, stability and repeatability, it has gradually become the research hotspot. Chitosan is an environment-friendly, abundant and recyclable natural polymer compound. The amino functional groups in molecular structure of chitosan have strong activity, which makes chitosan have various unique properties such as biodegradability, cell affinity and biological effects. It is widely used in the fields of medicine, food and environmental protection. The functional group of chitosan has strong reaction activity and is easy to be chemically modification. Combined with molecular imprinting technology, the chitosan and its derivatives could be taken as functional monomers or carriers for preparing new molecular imprinting polymers with ideal affinity and stability, high imprinting efficiency and strong selectivity, which can improve the properties of chitosan materials and broaden its application field and scope.
According to the research progress in the field of molecular imprinting modification of chitosan, the role of chitosan and its derivatives in the preparation of molecular imprinting polymers, the preparation methods of molecular imprinting polymers and the types of common crosslinking agents were summarized. The applications of chitosan molecular imprinting polymers in the treatment of heavy metal pollutants, biomedicine, solid phase extraction, protein recognition, electrochemical sensor and chiral material separation were expounded in detail. The advantages and disadvantages of chitosan molecular imprinting polymers in various fields were analyzed. The development direction of chitosan molecular imprinting technology was prospected.

Key words： chitosan molecular imprinting technique polymer functional monomer carrier

Published: 10 September 2022 Online: 2022-09-10

CLC number:

O636.1+2

Fund:National Natural Science Foundation of China (21406142), Natural Science Foundation of Liaoning Province (2020-MS-230), Scientific Research Project of Liaoning Provincial Department of Education (LJ2020036), and Shenyang Young and Middle-aged Scientific and Technological Talents Project(RC190323).

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	Articles by authors
	FENG Ying
	LI Qixue
	SHAO Juan
	ZHANG Jianwei
	DONG Xin
	ZHANG Qingjin

Cite this article:

FENG Ying,LI Qixue,SHAO Juan, et al. Research and Application of Molecular Imprinting Technology Based on Chitosan[J]. Materials Reports, 2022, 36(17): 21040121-8.

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http://www.mater-rep.com/EN/10.11896/cldb.21040121 OR http://www.mater-rep.com/EN/Y2022/V36/I17/21040121

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