介孔二氧化硅纳米颗粒作为药物载体的研究现状

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Abstract As a new inorganic material, mesoporous silica nanomaterials have many advantages such as high surface area, large pore volume and surface modification, which make them widely used in the field of biomedicine. However, the single mesoporous silica has some problems such as low biodegradation and single performance. To remedy these functional defects, a series of composite materials based on mesoporous silica nanoparticles emerged. Mesoporous silica shows controllable, stable characteristics when mixed with inorganic and organic materials, which greatly improves its properties. In this paper, different forms of mesoporous silica and their properties are reviewed, and the properties, research achievements and applications of mesoporous silica composites with inorganic and organic materials are summarized.

Key words： inorganic materials mesoporous nanoparticles silicon matrix composites silicon oxide drug carrier

Published: 05 June 2022 Online: 2022-06-08

CLC number:

TQ460.4

Fund:Shandong Provincial Natural Science Foundation (ZR2019PH048) and Shandong Province Students' Innovation and Entrepreneurship Training Program (S202110441021).

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	Articles by authors
	YANG Huishu
	LI Le
	LIU Xinyao
	TANG Kaixuan
	QIAO Li

Cite this article:

YANG Huishu,LI Le,LIU Xinyao, et al. Research Status of Mesoporous Silica Nanoparticles as Drug Carriers[J]. Materials Reports, 2022, 36(Z1): 21110245-6.

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http://www.mater-rep.com/EN/ OR http://www.mater-rep.com/EN/Y2022/V36/IZ1/21110245

1 Jiang H, Guo Y, Wei C, et al. Advanced Materials, 2021, 33(20), 1.
2 Lin F C, Xie Y, Deng T, et al. Journal of the American Chemical Society, 2021, 143(16), 6025.
3 贺旷驰,王蒙,赵斌, 等. 材料导报:综述篇, 2014, 28(7), 33.
4 韩静香,佘利娟,翟立新, 等. 材料导报, 2010, 24(S1), 6.
5 Jafari S, Derakhshankhah H, Alaei L, et al. Biomedicine and Pharmacotherapy, 2019, 109, 1100.
6 Wang J, Lu Z, Shen J, et al. Journal of Biomedical Nanotechnology, 2020, 16(5), 652.
7 Wu Y X, Zhang D, Hu X, et al. Angewandte Chemie International Edition, 2021, 60(22), 12569.
8 Miricioiu M G, Niculescu V C. Nanomaterials, 2020, 10(3), 474.
9 Hoang Thi T T, CaoV D, Nguyen T N Q, et al. Materials Science and Engineering C, 2019, 99, 631.
10 Luo S, Hao J, Gao Y, et al. Materials Science and Engineering C, 2019, 100, 789.
11 Juère E, Florek J, Bouchoucha M, et al. Molecular Pharmaceutics, 2017, 14(12), 4431.
12 Lyu Y, Li J, Chen H, et al. International Journal of Nanomedicine, 2017, 12, 4361.
13 Zhang K, Zhang Y H, Li Y, et al. Journal of Biomaterials Science, Polymer Edition, 2021, 32(6), 695.
14 Pérez-Garnes M, Gutiérrez-Salmerón M, Morales V, et al. Materials Science and Engineering C, 2020, 16(5), 652.
15 张硕. 材料导报, 2020, 34(S2), 1091.
16 Geng H, Chen W, Xu Z P, et al. European Journal of Medicinal Chemistry, 2017, 23(45), 10878.
17 冯雪风, 金卫根, 杨婥. 无机盐工业, 2009, 41(9), 18.
18 Ao L, Hu X, Xu M, et al. Dalton Transactions, 2020, 49(15), 4669.
19 Dai Y, Yang D, Yu D, et al. Nanoscale, 2020, 12(8), 5075.
20 王亚斌,刘忠,史时辉,等. 无机材料学报, 2018, 230(12), 1274.
21 Hou X, Fan W, Wang G, et al. Journal of Nanobiotechnology, 2020, 18(1), 1.
22 Tang J, Meka A K, Theivendran S, et al. Angewandte Chemie-International Edition, 2020, 59(49), 22054.
23 Cheng Y, Jiao X, Fan W, et al. Biomaterialsl, 2020, 256, 120191.
24 Shakeran Z, Keyhanfar M, Varshosaz J, et al. Materials Science and Engineering, C, 2021, 118, 111526.
25 Croissant J G, Fatieiev Y, Khashab N M, et al. Advanced Materials, 2017, 29(9), 1604634.
26 Tzankova V, Aluani D, Yordanov Y, et al. Drug and Chemical Toxicology, 2021, 44(3), 238.
27 Zhang L, Wang L, Wang L, et al. Journal of Materials Chemistry B, 2017, 5(39), 8013.
28 Wu J, Williams G R, Niu S, et al. Advanced Science, 2019, 6(4), 1802001.
29 Cheng S B, Xie M. University Chemistry, 2016, 31(11), 1.
30 Tufani A, Qureshi A, Niazi J H. Materials Science and Engineering C, 2021, 118, 111545.
31 Vangijzegem T, Stanicki D, Laurent S, et al. Expert Opinion on Drug Delivery, 2019, 16(1), 69.
32 Sun B, Zhen X, Jiang X. Biomaterials Science, 2021, 9(10), 3603.
33 Castillo R R, Vallet-Regí M. International Journal of Molecular Medicine, 2019, 20(4), 929.
34 Albinali K E, Zagho M M, Deng Y, et al. International Journal of Nanomedicine, 2019, 14, 1707.
35 Li E, Yang Y, Hao G, et al. Nanotheranostics, 2018, 2(3), 233.
36 Kong Y, Li X, Liu X, et al. Journal of Nanoscience and Nanotechnology, 2021, 21(9), 4553.
37 Elahi N, Kamali M, Baghersad M H, et al. Talanta, 2018, 184, 537.
38 Yang Z, Li Z, Lu X, et al. Nano-Micro Letters, 2017, 9(1), 1.
39 Lin Y, Ren J, Qu X, et al. Advanced Materials, 2014, 26(25), 4200.
40 Xin H, Zhang M, Wang M, et al. Langmuir, 2018, 34(12), 3642.
41 Kalantari M, Ghosh T, Liu Y, et al. ACS Applied Materials & Interfaces, 2019, 11(14), 13264.
42 Delpiano G R, Casula M F, Piludu M, et al. ACS Omega, 2019, 4(6), 11044.
43 Chen G, Xie Y, Peltier R, et al. ACS Applied Materials & Interfaces, 2016, 8(18), 11204.
44 Raji M, Hamid E, Denis R, et al. Polymers and Polymer Composites, 2017, 39(8), 2932.
45 Pandit S, Gaska K, Kádár R, et al. Chemphyschem, 2021, 22(3), 250.
46 胡洪亮, 张国. 高分子材料科学与工程, 2016, 32(2), 95.
47 Grajek H, Jonik J, Witkiewicz Z, et al. Critical Reviews in Analytical Chemistry, 2020, 50(5), 445.
48 Loutfy S A, Salaheldin T A, Ramadan M A, et al. Asian Pacific Journal of Cancer Prevention, APJCP, 2017, 18(4), 955.
49 Dong K, Zhao Z Z, Kang J, et al. International Journal of Nanomedicine, 2020, 15(17), 10285.
50 Tran A V, Shim K, Vo Thi T T, et al. Acta Biomaterialia, 2018, 74, 397.
51 Jiang X, Gray P, Patel M, et al. Journal of Materials Chemistry, 2020, 8(6), 1191.
52 Razumov I A, Troitsky S Y, Zavjalov E L, et al. Nanotechnologies in Russia, 2021, 15(11), 819.
53 Patra T, Mohanty A, Singh L, et al. Chemosphere, 2021, 288, 132472.
54 Bai B, Qiao Q, Li Y, et al. Chinese Journal of Catalysis, 2018, 39(4), 630.
55 Liu L, Liu Z, Chen Y, et al. Science of the Total Environment, 2021, 772, 144953.
56 Chen Y, Chen H, Zhang S, et al. Biomaterials, 2012, 33(7), 2388.
57 Du D, Fu H J, Ren W W, et al. Biomedicine & Pharmacotherapy, 2020, 121, 109614.
58 王思恒, 杨欣欣, 刘鹤, 等. 化工进展, 2021, 40(5), 2646.
59 Ahmed S, Alhareth K, Mignet N, et al. International Journal of Pharmaceutics, 2020, 584, 119435.
60 Yao J, Li T, Shi X, et al. Acta Biomaterialia, 2021, 130, 409.
61 Kinoshita N, Sasaki Y, Marukawa E, et al. Polymer Edition, 2020, 31(10), 1254.
62 Wechsler M E, Dang H K H J, Dahlhauser S D, et al. Chemical Communications, 2020, 56(45), 6141.
63 Qi M, Pan H, Shen H, et al. Angewandte Chemie-International Edition, 2020, 59(29), 11748.
64 Zengin A, Castro J P O, Habibovic P, et al. Nanoscale, 2020, 13(2), 1144.
65 Qiao L, Wang X, Gao Y, et al. Nanoscale, 2016, 8(39), 17241.
66 Thakor P, Bhavana V, Sharma R, et al. Drug Discovery Today, 2020, 25(9), 1718.
67 Saboo S, Kestur U S, Flaherty D P, et al. Molecular Pharmaceutics, 2020, 17(4), 1261.
68 Qin Y, Shan X, Han Y, et al. Journal of Nanoscience and Nanotechnology, 2020, 20(10), 5997.