环糊精衍生物水凝胶材料的研究进展

doi:10.11896/j.issn.1005-023X.2018.19.020

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Abstract Hydrogels are a kind of chemically or physically crosslinked polymer materials. The hydrophilic three-dimensional network structure endows hydrogels with the ability of absorbing and maintaining a large amount of water. Compared with other materials, hydrogels possess outstanding advantages including high water content, soft texture, excellent permeability and favorable biocompatibility, which enable the widespread application of hydrogels in industry, agriculture, biomedicine and even daily life. In recent years, researchers at home and abroad have devoted themselves to develop innovative hydrogels to overcome the poor mechanical strength and deficient function of traditional hydrogels. Therefore, numerous new hydrogels with multifunctional and high strength have emerged, such as temperature, pH, light, electromagnetic stimuli-responsive hydrogels, double networks, interpenetrating network hydrogels, nanocomposite hydrogels and self-healing hydrogel.
It is worth mentioning that the introduction of cyclodextrin and its derivatives is one of the important strategies to solve the deficiency of hydrogels. Cyclodextrin molecules contain special structure with hydrophilic outer rim, hydrophobic inner ring and hydrophobic cavities, which can accommodate hydrophobic molecules through host and guest interaction. In recent years, researchers have taken advantage of the unique structure and properties of cyclodextrins and intensive research endeavors have been put into designing cyclodextrin derivative hydrogels with superior structures and functions. And impressive strides have achieved that a series of cyclodextrin derivatives based hydrogels with excellent properties were developed.
Cyclodextrins derivatives based hydrogels not only show their superiority in terms of mechanical properties, but also have signi-ficant functions, like stimulus responsiveness, self-healing, shape memory, injectability, etc. Now, the reported cyclodextrin derivatives based hydrogels show diverse structures and various properties. They can be divided into four types according to their network structure: Ⅰ. mono-cyclodextrin crosslinked hydrogel; Ⅱ. host-guest supramolecular hydrogel; Ⅲ. cyclodextrin based double network hydrogel; Ⅳ. slide-ring hydrogel. The developments of cyclodextrin derivatives hydrogels with diverse cross-linked structures have create various functions and properties of hydrogels. Moreover, it provides a way to break through the bottlenecks of traditional hydrogels and broaden the application prospect in catalytic engineering, drug control release, bone/cartilage tissue repair and water pollutant purification.
This review offers a retrospection of the research efforts to cyclodextrin polymer hydrogels. Cyclodextrin derivative hydrogels are classified according to the cross-linked structure. And the elaboration about the structure, preparation and application of cyclodextrin molecules and cyclodextrin derivatives hydrogels are provided respectively. The problems and prospects of cyclodextrin derivatives hydrogels were analyzed in order to provide reference for the preparation of multifunctional, high-strength cyclodextrin derivatives hydrogels.

Key words： cyclodextrin derivatives hydrogels mechanical strength multifunctional

Published: 18 October 2018

CLC number:

TB324

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	WANG Zhifang
	XUAN Chengkai
	LIU Xuemin
	SHI Xuetao

Cite this article:

WANG Zhifang,XUAN Chengkai,LIU Xuemin, et al. Advances in Hydrogel Materials Based on Cyclodextrin Derivatives[J]. Materials Reports, 2018, 32(19): 3456-3464.

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http://www.mater-rep.com/EN/10.11896/j.issn.1005-023X.2018.19.020 OR http://www.mater-rep.com/EN/Y2018/V32/I19/3456

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